NCT04030897

Brief Summary

Major depression (MD) in youth is a serious psychiatric illness with extensive morbidity and mortality. The American Academy of Pediatrics recently released practice guidelines promoting primary care (PC)-based youth MD screening; however, even when diagnosed by PC providers, \<50% of youth with MD access treatment. Thus, a need exists for interventions that are feasible for youths and parents to access and complete-and that may strengthen parents' likelihood of pursuing longer-term services. Single-session interventions (SSIs) may help forward these goals. SSIs include elements of comprehensive treatments, but their brevity makes them easier to disseminate at scale. Meta-analytic evidence suggests SSIs can reduce youth psychopathology, including self-administered (e.g., online) SSIs. One computer-based SSI, teaching growth mindset (GM; viewing personal traits as malleable), has reduced adolescent depressive symptoms in multiple RCTs; GM-SSIs have also improved parents' expectancies that psychotherapy could benefit their children's mental health. This project will test whether these online, youth- and parent-directed GM-SSIs-designed to reduce youth depressive symptoms and improve parents' mental health treatment expectancies, respectively-may increase mental health service access, reduce youth depressive symptoms, and relieve parental stress following PC-based youth MD screening. Youths reporting elevated MD symptoms at PC visits (N = 200) will receive either Information/Psychoeducation/Referral (IPR) or IPR plus parent- and youth-directed GM-SSIs (IPR+SSI). The investigators will examine whether IPR+SSI, versus IPR alone, increases MD service access; reduces parental stress; and reduces youth depressive symptoms across three months. Results may yield a disseminable model for promoting youth treatment access after PC-based depression screening.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
246

participants targeted

Target at P75+ for not_applicable depression

Timeline
Completed

Started Jan 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 20, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 24, 2019

Completed
6 months until next milestone

Study Start

First participant enrolled

January 15, 2020

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2021

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2021

Completed
Last Updated

March 6, 2020

Status Verified

March 1, 2020

Enrollment Period

1.3 years

First QC Date

July 20, 2019

Last Update Submit

March 5, 2020

Conditions

Outcome Measures

Primary Outcomes (2)

  • Mental Health Treatment-Seeking Behavior Checklist

    At baseline and 3-month follow-up, parents will indicate whether they have engaged in each of four treatment-seeking behaviors for their child: researched local mental healthcare providers/agencies for their child; contacted a mental healthcare provider or agency about treatment for their child; contacted child's school regarding mental health supports for their child; and scheduled an appointment OR placed child on a waiting-list with a mental healthcare provider/agency. Total number of treatment-seeking behaviors between baseline and 3-month follow-up may range from 0 to 4. Individual behaviors are self-reported by parents on as 'yes' or 'no' (noting whether they engaged in the behavior during the study period). At baseline, parents will report on whether they engaged in these behaviors 'since the child's last doctor's appointment.' At follow-up, parents will report whether they have engaged in these behaviors 'since their past survey, 3 months ago.'

    Baseline to 3-month follow-up

  • Change in Children's Depression Inventory 2 - Youth Report Total Score

    Change in youth reported depressive symptoms, total score derived from 28-item CDI-2. Scores range from 0-56, with higher scores indicating higher levels of depression.

    Baseline to 3-month follow-up.

Secondary Outcomes (12)

  • Change in Pediatric Symptom Checklist - Youth-Report Total score

    Baseline to 3-month follow-up.

  • Change in Pediatric Symptom Checklist- Parent Report Total score

    Baseline to 3-month follow-up.

  • Change in Pediatric Symptom Checklist- Youth Internalizing Score (parent report)

    Baseline to 3-month follow-up.

  • Change in Beck Hopelessness Scale - 4 (Youth Report)

    Baseline to immediate post-online-intervention (in active intervention group only) and 3-month follow-up (between groups).

  • Change in Beck Hopelessness Scale - 4 (Parent Report)

    Baseline to immediate post-online-intervention (in active intervention group only) and 3-month follow-up (between groups).

  • +7 more secondary outcomes

Other Outcomes (2)

  • Change in implicit theories of emotion scale, parent-report

    Baseline to immediate-post-online intervention (active intervention group only)

  • Change in Implicit Theories of Personality Questionnaire, youth-report

    Baseline to immediate-post-online intervention (active intervention group only)

Study Arms (2)

Online Programs + Information/Psychoeducation/Referral (IPR)

ACTIVE COMPARATOR

Includes 2 online, one-session programs (one for youths; one for parents) and Primary Care-based IPR. The 30-min, self-administered YOUTH PROGRAM includes: An introduction to the brain and a lesson on neuroplasticity; Testimonials from older youths who describe their views that traits are malleable, due to the brain's plasticity; Further stories by older youths, describing times when they used "growth mindsets" to persevere during social/emotional setbacks; Study summaries noting how/why personality can change; And an exercise in which youths write notes to younger students, using scientific information to explain people's capacity for change. In the 15-min Qualtrics-based PARENT PROGRAM, parents read 2 scientific passages on (1) the notion that emotions are flexible in youth and adults, and (2) that failure promotes personal growth. After each passage, parents write a persuasive summary of its main arguments, directed to fellow parents who may benefit from the information.

Behavioral: Parent-Directed Online Single-Session ProgramBehavioral: Youth-Directed Online Single-Session ProgramBehavioral: Information/Psychoeducation/Referral

Information/Psychoeducation/Referral (IPR; usual care control)

PLACEBO COMPARATOR

Information, Psychoeducation and Referral (IPR) represents usual care in the Stony Brook University Hospital's Pediatric Primary Care Division. Families of a youth with elevated MD symptoms during a PC visit receive a folder containing informational materials about the nature of depression and referrals to providers in their area. All families in this study will receive PC-based IPR.

Behavioral: Information/Psychoeducation/Referral

Interventions

Online, 15-minute self-administered program for parents

Online Programs + Information/Psychoeducation/Referral (IPR)

Online, 30 minute self-administered program for youths

Also known as: Project Personality
Online Programs + Information/Psychoeducation/Referral (IPR)

Usual care at pediatric primary care clinics participating in this study

Information/Psychoeducation/Referral (IPR; usual care control)Online Programs + Information/Psychoeducation/Referral (IPR)

Eligibility Criteria

Age11 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Youth is between the ages of 11 and 16, inclusive, at the time of study recruitment
  • Youth reports a Pediatric Symptom Checklist 'Internalizing' score of 5 or higher (out of 10) at her/his most recent pediatric primary care visit at 1 of the 9 Stony Brook University-affiliated clinics participating in this study
  • Parent and youth are comfortable with reading and writing in English
  • Parent and youth are comfortable with online activity

You may not qualify if:

  • Parent or youth is not comfortable reading and/or writing in English
  • Parent or youth is not comfortable with online activity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stony Brook University

Stony Brook, New York, 11794-2500, United States

RECRUITING

Related Publications (1)

  • Schleider JL, Dobias M, Fassler J, Shroff A, Pati S. Promoting Treatment Access Following Pediatric Primary Care Depression Screening: Randomized Trial of Web-Based, Single-Session Interventions for Parents and Youths. J Am Acad Child Adolesc Psychiatry. 2020 Jun;59(6):770-773. doi: 10.1016/j.jaac.2020.01.025. Epub 2020 Apr 28. No abstract available.

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Officials

  • Jessica Schleider, PhD

    Stony Brook University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Participating youths and parents will be aware of whether they are receiving the online interventions immediately or after the 3-month follow-up period (i.e., whether they are in the 'intervention group' or the 'waitlist group'). However, participating families will be assigned to these conditions via an online survey, which they complete remotely, and condition assignments will be unknown to the research team and the youth's primary care provider.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Youths reporting elevated MD symptoms at a PC visit (N = 200) will be randomly assigned to one of two conditions (within a waitlist-control design): Information, Psychoeducation, and Referral (IPR; ie., usual care, or the "control") or IPR enhanced with youth- and parent-directed online SSIs (IPR+SSI), designed to reduce youth MD symptoms and improve parents' expectancies of mental health treatment, respectively.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Psychology

Study Record Dates

First Submitted

July 20, 2019

First Posted

July 24, 2019

Study Start

January 15, 2020

Primary Completion

April 30, 2021

Study Completion

August 30, 2021

Last Updated

March 6, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will share

De-identified individual-level participant data will be made publicly available on Open Science Framework upon completion of the grant period (August 2021).

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Study protocol and a statistical analysis plan have been uploaded with this pre-registration.
Access Criteria
Materials will be publicly available on clinicaltrials.gov. IPD will be made publicly available on Open Science Framework upon completion of the grant period (August 2021)

Locations