Platelet Activity in T2DM Using Flowcytometry
Platelet Activity in Type 2 Diabetic Patients Using Flowcytometry in Relation to Macrovascular Complication.
1 other identifier
observational
122
0 countries
N/A
Brief Summary
-Describe platelet activity in type 2 diabetes as a participant in vascular inflammation. -Compare platelet activity in patients with type 2 diabetes mellitus versus healthy controls. -Study and describe platelet activity in patients with type 2 diabetes mellitus in association with ischemic cardiovascular disease in relation to duration of diabetes mellitus .
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2019
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 18, 2019
CompletedFirst Posted
Study publicly available on registry
July 22, 2019
CompletedStudy Start
First participant enrolled
October 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2021
CompletedJuly 22, 2019
July 1, 2019
2 years
July 18, 2019
July 18, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Platelet activity in type 2 diabetic patients using flowcytometry in relation to macrovascular complication.
Dedect platelet activity by surface expression of platelet receptors determined by flowcytometry using different monoclonal antibodies (CD62 and CD63)
Baseline
Secondary Outcomes (1)
Platelet activity in type 2 diabetic patients using flowcytometry in relation to macrovascular complication.
Baseline
Study Arms (2)
T2DM
healthy controls
Interventions
detect platelet activity in T2DM by surface expression of platelet receptors determined by flowcytometry using different monoclonal antibodies (CD62 and CD63).
Eligibility Criteria
Diabetic patients will be recruited from Internal medicine department and Diabetes out patient clinic in Assuit University Hospital. Controls will be health workers and paramedicals in Assuit university hospital.
You may qualify if:
- The study will include patient with type II diabetes at age of 30-60 years old with or without ischemic cardiovascular disease. . Controls will be healthy individuals with normal blood glucose level of same matched age group.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (3)
Castaigne F, Liber E, Carbillet L, Boulet M, Riel RR. [New procedure for protein spinning: the hydrodynamic process]. Ann Nutr Aliment. 1978;32(2-3):217-31. French.
PMID: 707914RESULTGulati RB, Wadia RS, Shaikh RA, Soares PM, Grant KB. Precordial mapping in acute myocardial infarction. Jpn Heart J. 1977 Jul;18(4):447-56. doi: 10.1536/ihj.18.447.
PMID: 909154RESULTGheorghiu T, Badescu A. [Dynamcis of immunocompetent cells in the contralateral lymph node in grafted cancer, under the influence of some factors stimulating and inhibiting the CNS in rats]. Rev Med Chir Soc Med Nat Iasi. 1976 Jan-Mar;80(1):79-84. No abstract available. Romanian.
PMID: 9680RESULT
Study Officials
- PRINCIPAL INVESTIGATOR
hanaa ahmed, master
Assiut University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- HMAmed
Study Record Dates
First Submitted
July 18, 2019
First Posted
July 22, 2019
Study Start
October 1, 2019
Primary Completion
October 1, 2021
Study Completion
December 1, 2021
Last Updated
July 22, 2019
Record last verified: 2019-07