Clinical Evaluation of WaterLase (iPlus) Laser Therapy Used as an Adjunct to Non-Surgical Treatment of Chronic Periodontitis: A Randomized, Controlled, Split-Mouth Clinical Study
Sponsor study identifier
interventional
23
0 countries
N/A
Study Start
January 2017
Actual (reported)Primary Completion
December 2019
Actual (reported)Study Completion
December 2019
Actual (reported)The use of lasers to treat various problems in dentistry is growing as it has in medicine. One application is the use of lasers to treat periodontal disease. It has been suggested that the laser may reduce the need for surgical treatment by reducing pockets. The goal of this study is to evaluate the effectiveness of laser treatment for periodontal disease. Laser therapy will be used in addition to traditional non-surgical scaling and root planing (deep cleaning). The information obtained from this study will provide an objective assessment of adjunctive laser therapy compared to conventional periodontal therapy and will attempt to show the benefits, if any, lasers can provide in the treatment of chronic periodontal disease.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2017
Actual (reported)July 18, 2019
Actual (reported)July 22, 2019
Actual (reported)December 2019
Actual (reported)December 2019
Actual (reported)March 5, 2021
Actual (reported)Probing Pocket Depth
This is a measure from base of pocket to gingival margin.
12 months
Sites That Bleed on Probing
Percentage of sites that bleed in response to probing. Bleeding observed within 30 seconds from pocket/sulcus following periodontal probe measurement.
12 months
Gingival Recession
Measure of gingival recession following treatment. This is a measure of the gingival margin from the cement-enamel junction.
12 months
Clinical Attachment Level
Periodontal clinical attachment level following treatment. This is a calculation (clinical attachment level = probing pocket depth + gingival recession).
12 months
Periodontal Microbiome
12 months
Patient Reported Outcomes: VAS Questionnaire
12 months
Laser therapy used as an adjunct to scaling and root planing
Scaling and root planing used as conventional non-surgical periodontal therapy
Adjunctive application of laser therapy in the periodontal pocket
Scaling to remove calculus deposits and root planing to smooth root surfaces
Perry R Klokkevold, DDS, MS
UCLA School of Dentistry, Section of Periodontics
23 participants (actual enrollment reported by the registry).
First Submitted
July 18, 2019
First Posted
July 22, 2019
Study Start
January 2017
Actual (reported)Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
December 2019
Actual (reported)Study Completion
December 2019
Actual (reported)Last Updated
March 5, 2021
Results First Posted
March 5, 2021
Record last verified: 2021-02
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Source: ClinicalTrials.gov.
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