NCT04018742

Brief Summary

Establish the repertoire of bacteria and Archaea responsible for brain abscesses. Correlate the microbial repertoire to epidemiological, clinical and radiological data; to define the different nosological entities falling within the framework of cerebral abscesses.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2019

Longer than P75 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 9, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 12, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

October 1, 2019

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2022

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2023

Completed
Last Updated

July 16, 2019

Status Verified

July 1, 2019

Enrollment Period

3 years

First QC Date

July 9, 2019

Last Update Submit

July 12, 2019

Conditions

Brain Abscess

Outcome Measures

Primary Outcomes (1)

  • Matrix Assisted Laser Desorption Ionisation - Time of Flight

    A matrix and a sample are deposited on a target. Pulsed lasers are fast charging.

    1 day

Study Arms (1)

Patients with an abscess

Patient diagnosed with a cerebral abscess at admission; and to benefit from an abscess puncture as part of routine care.

Other: Surgical puncture

Interventions

Surgical punctureOTHER

Investigators propose to collect 20 abscesses. A collection of abscesses is performed systematically during the diagnostic for bacteriological analysis. There will be no further examination.

Patients with an abscess

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patient diagnosed with a cerebral abscess at admission; and to benefit from an abscess puncture as part of routine care.

You may qualify if:

  • Patient diagnosed with a cerebral abscess at admission; and to benefit from an abscess puncture as part of routine care.
  • Affiliate or beneficiary of a social security scheme.

You may not qualify if:

  • Pregnant or nursing woman.
  • Major patient under tutorship or curatorship.
  • Patient deprived of liberty or under a court order
  • Patient refusing to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Brain Abscess

Condition Hierarchy (Ancestors)

Central Nervous System InfectionsInfectionsAbscessSuppurationBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Didier Raoult

CONTACT

04 13 73 20 51didier.raoult@gmail.com

Alexandra Giuliani

CONTACT

04 91 38 28 70promotion.interne@aphm.fr

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 9, 2019

First Posted

July 12, 2019

Study Start

October 1, 2019

Primary Completion

September 30, 2022

Study Completion

October 30, 2023

Last Updated

July 16, 2019

Record last verified: 2019-07