Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia

NCT04017182 | Unknown

• 1 other identifier: 04072019
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

After installation of central venous catheter in patients under general anesthesia, paired sample of superior vena cava central venous blood and right external jugular venous blood will be collected and send to central laboratory for venous blood gas analysis. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined as primary outcome.

Conditions

Central Venous Oxygen Saturation

Keywords

central venous oxygen saturation; external jugular venous oxygen saturation; central venous catheter; external jugular vein; internal jugular vein; superior vena cava oxygen saturation

Outcome Measures

Primary Outcomes (1)

• Correlation of venous oxygen saturation

  Correlation of venous oxygen saturation between external jugular vein and superior vena cava

  1 hour

Secondary Outcomes (2)

• Correlation of venous partial pressure of carbon dioxide

  1 hour

• Relationship between superior vena cava central venous and external jugular venous oxygen saturation

  1 hour

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult surgical patients undergoing surgery under general anesthesia in institutional operating theaters with superior vena cava central venous catheter installation anticipated.

You may qualify if:

• Written consent obtained from patient or next of kin a day before operation date
• Patient age between 18-65 years old undergoing syrgery under general anesthesia
• Superior vena cava central venous catheter anticipated for CVP mesurement, innotropic or vasopressor administration,pulmonary artery catheter insertion route
• Anticipated right external jugular venous sampling time less than 5 minutes
• The site of blood sample collection easily access during operation

You may not qualify if:

• No jugular central venous catheter installation or other route selected
• Duration of paired sample collection more than 10 minutes
• Can not collected blood sample from right external jugular vein within 3 attemps
• The site of blood sample collection difficulty access during operation
• Pateint or next of kin refuse to participate

Sponsors & Collaborators

• Ramathibodi Hospital: lead

Study Sites (1)

Department of Anesthesiology, Ramathibodi Hospital

Bangkok, Bangkok, 10400, Thailand

Location

Central Study Contacts

Thanist Pravitharangul, MD

CONTACT

66866633694; thnst_yu@msn.com

Cherdkiat Karnjanarachata, MD

CONTACT

66855774747; chird_na@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: July 4, 2019
• First Posted: July 12, 2019
• Study Start: April 1, 2021
• Primary Completion: December 1, 2021
• Study Completion: December 1, 2021
• Last Updated: March 9, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share

Locations

TH (1)