NCT04010721

Brief Summary

The aim of this study is to investigate the effect of varying additional factors on loudness summation in Neuro Zti Cochlear Implant users.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 2, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 8, 2019

Completed
7 months until next milestone

Study Start

First participant enrolled

February 10, 2020

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 25, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 25, 2020

Completed
Last Updated

October 20, 2021

Status Verified

October 1, 2021

Enrollment Period

7 months

First QC Date

July 2, 2019

Last Update Submit

October 13, 2021

Conditions

Keywords

Cochlear implant

Outcome Measures

Primary Outcomes (1)

  • Experiment 2: the effect of number of electrodes on loudness

    Changes in electrical charge (nC) needed to achieve C-level and T-level. The charge is the results of Intensity\*Duration of a pulse, in µA and µs respectivelly. If either the amplitude or the duration of the pulse is modified, the charge will be modified as well.

    2 hours

Secondary Outcomes (2)

  • Experiment 1 : the effect of pulse amplitude and pulse duration on loudness

    2 hours

  • Experiment 3 : the effect of stimulation duration on loudness

    2 hours

Study Arms (1)

Experimental : experiment 1,2 and 3

OTHER

One user included participates all experiments: * Visit 1 : experiment 1 * Visit 2 : experiment 2 * Visit 3 : experiment 3

Device: Experiment 1Device: Experiment 2:Device: Experiment 3

Interventions

Stimulation of one electrode at a time

Experimental : experiment 1,2 and 3

Stimulation in groups of 4, 8 and 12 electrodes

Experimental : experiment 1,2 and 3

Stimulation total duration from 10 to 600 ms

Experimental : experiment 1,2 and 3

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Neuro One or Neuro 2 user
  • Unilateral or bilateral recipient
  • months CI experience to allow for acclimatization to the CI sound processing and pathological changes that could alter the electrode - tissue interface and therefore T- \& C-levels.
  • Having at least 7 step sizes on three electrodes in their current clinical map (for experimentation 1).
  • Able and willing to provide reliable threshold and comfort level judgements

You may not qualify if:

  • Medical conditions that contraindicate the study tests (e.g. tinnitus, dizziness)
  • Unrealistic expectations from the candidate regarding the possible benefits, risks, and limitations that are inherent to the device
  • Unwillingness or inability of the candidate to comply with all investigational requirements
  • Vulnerable population

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Lille

Lille, 59000, France

Location

MeSH Terms

Conditions

Hearing Loss, Sensorineural

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Christophe VINCENT

    CHRU LILLE

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 2, 2019

First Posted

July 8, 2019

Study Start

February 10, 2020

Primary Completion

August 25, 2020

Study Completion

August 25, 2020

Last Updated

October 20, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

Locations