NCT04007432

Brief Summary

Delirium is a common complication following hip fracture surgery (HFS) in older people. Postoperative hypoxia has also been associated with delirium, but not specifically in geriatric patients. The aim of the study is to demonstrate that post-operative hypoxia is associated with in-hospital complications in patients with HFS.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
30mo left

Started Nov 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress69%
Nov 2020Nov 2028

First Submitted

Initial submission to the registry

June 18, 2019

Completed
17 days until next milestone

First Posted

Study publicly available on registry

July 5, 2019

Completed
1.3 years until next milestone

Study Start

First participant enrolled

November 5, 2020

Completed
8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 5, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 5, 2028

Last Updated

May 4, 2026

Status Verified

April 1, 2026

Enrollment Period

8 years

First QC Date

June 18, 2019

Last Update Submit

April 28, 2026

Conditions

Keywords

nocturnal hypoxiadelirum developpement

Outcome Measures

Primary Outcomes (1)

  • Delirium

    Delirum or not, diagnosed with CAM (Confusion Assessment Method). Association between nocturnal hypoxia and delirium will be study.

    Month 1

Secondary Outcomes (11)

  • In-hospital complications

    Month 1

  • Length of hospitalisation stay in othogeriatrics unit

    Month 1

  • walking status (functional status)

    Month 1

  • walking status (functional status)

    Month 1

  • walking speed (functional status)

    Month 1

  • +6 more secondary outcomes

Study Arms (1)

Older patients with hip fracture

EXPERIMENTAL

Older patients admitted for hip fracture surgery

Other: pulse oxymeter

Interventions

Nocturnal oxymetry data will be continuously collected during nighttime by a pulse oxymeter, covering for 1 to 3 nights.

Older patients with hip fracture

Eligibility Criteria

Age70 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • age over 70 years old,
  • hospitalized in orthogeriatrics for hip fracture surgery
  • information about the study and expression of non opposition
  • Expected hospital stay of 5 nights or more

You may not qualify if:

  • patient under guardianship,
  • any other type of fracture associated,
  • oxymetry recording not possible (behavioral disorders, night stirring,...)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Service de gériatrie, Hopital Saint Antoine

Paris, 75012, France

RECRUITING

Service de Gériatrie Hopital de La Pitié Salpetriere

Paris, 75013, France

RECRUITING

MeSH Terms

Conditions

DeliriumHypoxia

Condition Hierarchy (Ancestors)

ConfusionNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurocognitive DisordersMental DisordersSigns and Symptoms, Respiratory

Study Officials

  • Kiyoka KINUGAWA

    Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 18, 2019

First Posted

July 5, 2019

Study Start

November 5, 2020

Primary Completion (Estimated)

November 5, 2028

Study Completion (Estimated)

November 5, 2028

Last Updated

May 4, 2026

Record last verified: 2026-04

Locations