NCT04004520

Brief Summary

The study will examine changes in acute stress (biological and psychological) via salivary cortisol and alpha amylase levels as well as survey measures of self-reported anxiety in response to either (a) a free online guided mindfulness meditation available at (https://www.uclahealth.org/marc/mindful-meditations); (b) a guided mindfulness meditation via virtual reality (https://guidedmeditationvr.com/) or (c) a virtual reality platform of historic photographs and written narratives (https://lookingglassvr.com/). Participants will also complete an interviewer administered survey to measure sociodemographic factors, mental and physical health status, substance use, and medication use and provide a hair sample to measure cortisol.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 28, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 2, 2019

Completed
22 days until next milestone

Study Start

First participant enrolled

July 24, 2019

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 8, 2019

Completed
11 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 19, 2019

Completed
Last Updated

July 13, 2022

Status Verified

July 1, 2022

Enrollment Period

15 days

First QC Date

June 28, 2019

Last Update Submit

July 12, 2022

Conditions

Keywords

stresscortisolalpha-amylasehomelessnessbiomarkersvirtual realitymeditation

Outcome Measures

Primary Outcomes (1)

  • Change in Stress Reactivity

    Participant gives the first saliva sample at arrival, then the second saliva sample 5 minutes after arrival prior to the intervention. The intervention is administered (approximately 10-15 minutes in length). The participant will give the third saliva sample immediately after the intervention and then a fourth saliva sample 15 minutes after the intervention.

    Baseline, 5 minutes, 20 minutes, 35 minutes

Secondary Outcomes (1)

  • Change in Self-reported Anxiety as measured by the Spielberger State-Trait Anxiety Inventory

    5 minutes, 35 minutes

Study Arms (3)

Virtual Reality with Meditation

EXPERIMENTAL

Participants will receive a virtual reality and audio guided mindfulness meditation program available at (https://guidedmeditationvr.com/)

Behavioral: Virtual Reality with Meditation

Virtual Reality Control

OTHER

Participants will receive a virtual reality of historic photographs and written narratives program (https://lookingglassvr.com/)

Behavioral: Virtual reality Control

Audio Control

OTHER

Participants will receive an online audio-only guided mindfulness meditation available at (https://www.uclahealth.org/marc/mindful-meditations).

Behavioral: Audio Control

Interventions

The Guided Meditation Virtual Reality is a mindfulness meditation app provided on a virtual reality platform that includes a 10 minute audio meditation for relaxation along with a 3D visualization of natural settings (e.g. forest, beach, mountain).

Also known as: Guided Meditation Virtual Reality
Virtual Reality with Meditation
Audio ControlBEHAVIORAL

The UCLA Mindful App is an audio only mindfulness meditation for relaxation called Breath, Sound, Body Meditation that is 12 minutes in length.

Also known as: UCLA Mindful App
Audio Control

The Looking Glass Virtual Reality is a stereographic 3D photo viewer provided on a virtual reality platform featuring photos from around the world dating back to approximately a century ago that participants will view for 10 minutes.

Also known as: Looking Glass Virtual Reality
Virtual Reality Control

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Between the ages of 18 to 24 years
  • Meets the criteria for homelessness as defined by the federal McKinney-Vento Act as "lacking a fixed, regular, stable, and adequate nighttime residence" and includes "living in a publicly or privately operated shelter designed to provide temporary living accommodations, or a public or private place not designed for, or ordinarily used as, regular sleeping accommodations for human beings"
  • speaks and understands the English language

You may not qualify if:

  • years and younger
  • years and older
  • non-English speakers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Ohio State University

Columbus, Ohio, 43210, United States

Location

Related Publications (1)

  • Chavez LJ, Kelleher K, Slesnick N, Holowacz E, Luthy E, Moore L, Ford J. Virtual Reality Meditation Among Youth Experiencing Homelessness: Pilot Randomized Controlled Trial of Feasibility. JMIR Ment Health. 2020 Sep 24;7(9):e18244. doi: 10.2196/18244.

Related Links

MeSH Terms

Interventions

Meditation

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesRelaxation TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Jodi L Ford, PhD

    Ohio State University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 28, 2019

First Posted

July 2, 2019

Study Start

July 24, 2019

Primary Completion

August 8, 2019

Study Completion

August 19, 2019

Last Updated

July 13, 2022

Record last verified: 2022-07

Data Sharing

IPD Sharing
Will not share

Locations