NCT03996161

Brief Summary

We compare the effect on semi-sitting position on mask ventilation in anesthetized and paralyzed obese patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 20, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 24, 2019

Completed
9 months until next milestone

Study Start

First participant enrolled

March 9, 2020

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 8, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 8, 2020

Completed
Last Updated

June 11, 2020

Status Verified

June 1, 2020

Enrollment Period

3 months

First QC Date

June 20, 2019

Last Update Submit

June 8, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Expiratory tidal volume

    Expiratory tidal volume is assessed during mask ventilation in the supine and semi-sitting positions.

    1 minute after the induction of anesthesia

Secondary Outcomes (3)

  • Minute ventilation during mask ventilation in the supine and semi-sitting positions

    1 minute after anesthesia induction

  • The incidence of inadequate mask ventilation or dead space ventilation.

    during mask ventilation

  • Peak inspiratory pressure

    during mask ventilation

Study Arms (2)

Supine position

ACTIVE COMPARATOR

After the induction of anesthesia, mask ventilation is performed in the supine position.

Other: patient position

Semi-sitting position

EXPERIMENTAL

After the induction of anesthesia, mask ventilation is performed in the semi-sitting position.

Other: patient position

Interventions

After the induction of anesthesia, mask ventilation is performed in the supine and semi-sitting position in a cross-over, randomized order.

Semi-sitting positionSupine position

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Obese patients undergoing general anesthesia

You may not qualify if:

  • diseases or structural abnormalities in the upper airway
  • those who were at risk of aspiration
  • cardiovascular or respiratory diseases
  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SMG-SNU Boramae Medical Center

Seoul, South Korea

Location

Related Publications (1)

  • Chang JE, Seol T, Hwang JY. Body position and the effectiveness of mask ventilation in anaesthetised paralysed obese patients: A randomised cross-over study. Eur J Anaesthesiol. 2021 Aug 1;38(8):825-830. doi: 10.1097/EJA.0000000000001473.

MeSH Terms

Conditions

Respiratory Aspiration

Interventions

Patient Positioning

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate professor

Study Record Dates

First Submitted

June 20, 2019

First Posted

June 24, 2019

Study Start

March 9, 2020

Primary Completion

June 8, 2020

Study Completion

June 8, 2020

Last Updated

June 11, 2020

Record last verified: 2020-06

Locations