NCT03992950

Brief Summary

Comparing the effects of 'Cricoid pressure' or 'Paratracheal pressure' during direct laryngoscopy

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 19, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 20, 2019

Completed
2.2 years until next milestone

Study Start

First participant enrolled

September 1, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 25, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 25, 2022

Completed
Last Updated

February 10, 2022

Status Verified

February 1, 2022

Enrollment Period

5 months

First QC Date

June 19, 2019

Last Update Submit

February 8, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Occlusion of the esophagus

    Occlusion of the esophagus is checked with the application of cricoid and paratracheal pressures using esophageal stethoscope. If the esophageal stethoscope is not advanced into the esophagus, it is considered 'occlusion'.

    During 1 minute under videolaryngoscopy

Secondary Outcomes (4)

  • Outer diameter of the esophagus

    During 1 minute after injection of anesthetics during induction of anesthesia

  • Position of the oesophageal entrance relative to the glottis

    During 1 minute after injection of anesthetics during induction of anesthesia and during videolaryngoscopy

  • Position of the upper oesophagus relative to the trachea

    During 1 minute after injection of anesthetics during induction of anesthesia and during videolaryngoscopy

  • The best laryngeal view

    Before and after the application of cricoid and paratracheal force during videolaryngoscopy

Study Arms (2)

Cricoid pressure

EXPERIMENTAL

Cricoid pressure is applied in the anesthetized state and during video laryngoscopy

Other: Maneuvers for occluding esophagus

Paratracheal pressure

EXPERIMENTAL

Paratracheal pressure is applied in the anesthetized state and during video laryngoscopy

Other: Maneuvers for occluding esophagus

Interventions

Cricoid pressure: pressure on the cricoid ring Paratracheal pressure: pressure on the left paratracheal region below the cricoid level

Cricoid pressureParatracheal pressure

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Who would be scheduled any surgery under general anesthesia and agree with the purpose of the study

You may not qualify if:

  • Risk of aspiration
  • History of esophageal surgery
  • Diseases or anatomical abnormalities of the neck, larynx, pharynx or esophagus
  • Known or predicted difficult airway.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul Metropolitan Government Seoul National University Boramae Medical Center

Seoul, 156-707, South Korea

Location

Related Publications (1)

  • Kim H, Chang JE, Won D, Lee JM, Kim TK, Kim MJ, Min SW, Hwang JY. Effectiveness of Cricoid and Paratracheal Pressures in Occluding the Upper Esophagus Through Induction of Anesthesia and Videolaryngoscopy: A Randomized, Crossover Study. Anesth Analg. 2022 Nov 1;135(5):1064-1072. doi: 10.1213/ANE.0000000000006154. Epub 2022 Aug 1.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate professor

Study Record Dates

First Submitted

June 19, 2019

First Posted

June 20, 2019

Study Start

September 1, 2021

Primary Completion

January 25, 2022

Study Completion

January 25, 2022

Last Updated

February 10, 2022

Record last verified: 2022-02

Locations