NCT03985930

Brief Summary

This is a multicenter, randomized, clinical trial comparing treatment as usual to distraction with video projection or virtual reality in the management of pediatric (3-6 years) pain associated with venipuncture, intramuscular injection, and vaccination.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
122

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 11, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 14, 2019

Completed
1.4 years until next milestone

Study Start

First participant enrolled

November 1, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
Last Updated

April 3, 2023

Status Verified

March 1, 2023

Enrollment Period

1 year

First QC Date

June 11, 2019

Last Update Submit

March 29, 2023

Conditions

Keywords

Child, PreschoolVirtual RealityProcedural PainPhlebotomyVaccination

Outcome Measures

Primary Outcomes (1)

  • LLANTO Pain level: LLANTO pain scale

    Overall pain assessment using the LLANTO pain scale (Mild: 0-3, Moderate 4-6, Intense 7-10) For more information about LLANTO scale, please visit DOI: 10.1016/j.anpedi.2010.08.005

    Immediately after procedure

Secondary Outcomes (6)

  • LLANTO Crying

    Immediately after procedure

  • LLANTO Attitude

    Immediately after procedure

  • LLANTO Breathing

    Immediately after procedure

  • LLANTO Facial expression

    Immediately after procedure

  • LLANTO Postural muscle tone

    Immediately after procedure

  • +1 more secondary outcomes

Study Arms (2)

Distraction Group

EXPERIMENTAL

Children between the ages of 3 and 5 years will be distracted using virtual reality content delivered through goggles.

Device: Distraction with virtual reality

Treatment as Usual

ACTIVE COMPARATOR

Children randomized to this group will receive the usual medical care.

Other: Treatment as Usual

Interventions

Distraction content delivered through virtual reality goggles

Distraction Group

Treatment as Usual

Treatment as Usual

Eligibility Criteria

Age3 Years - 5 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Patients subjected to procedures of venipuncture, intramuscular injections, or vaccination at participating medical centers.

You may not qualify if:

  • Fever (Axillary temperature greater than 38°C).
  • Systemic Inflammatory Response Syndrome or Sepsis.
  • Pulmonary disease.
  • Neurological deficit of any kind.
  • Susspected or confirmed metabolic disease.
  • Undernutrition or obesity as defined by deviations from the mean of local values.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fundación Universitaria Sanitas

Bogotá, Bogota D.C., 111321, Colombia

Location

Related Publications (1)

  • Camacho-Cruz J, Palacios-Ariza MA, Orrego-Celestino L, Valbuena-Velandia N, Paez-Castellanos L, Bolanos JM, Pradilla I. Effectiveness of non-immersive virtual reality in the management of procedure-related pain in preschool children: a randomized clinical trial. Eur J Pediatr. 2023 Sep;182(9):4103-4112. doi: 10.1007/s00431-023-05070-5. Epub 2023 Jul 5.

MeSH Terms

Conditions

Pain, Procedural

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jhon H Camacho Cruz, M.D.

    Fundación Universitaria Sanitas

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Coordinadora Unidad de Investigación

Study Record Dates

First Submitted

June 11, 2019

First Posted

June 14, 2019

Study Start

November 1, 2020

Primary Completion

November 1, 2021

Study Completion

December 1, 2021

Last Updated

April 3, 2023

Record last verified: 2023-03

Data Sharing

IPD Sharing
Will not share

Locations