Chronic Kidney Disease and Cardiovascular Disease Risk Assessment

NCT03975439 | Withdrawn

• 1 other identifier: 2019-004
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study will investigate chronic kidney disease (CKD) and cardiovascular disease (CVD) risk factors in a sample population of Hispanics/Latinos and Caucasians in Yakima county that are rural dwelling. This investigation is intended to provide information on the impact rural geographical location and social determinants of health (SDOH) have on CKD and CVD risk factors.

Conditions

Chronic Kidney Diseases; Diabetes Mellitus; Hypertension

Outcome Measures

Primary Outcomes (1)

• Incidence of undiagnosed chronic kidney disease in farmworkers in Yakima County, WA

  Finger stick and urinalysis will be done at the time of screening

  At the time of screening

Secondary Outcomes (2)

• Incidence of undiagnosed diabetes mellitus in farmworkers in Yakima County, WA

  At the time of screening

• Incidence of undiagnosed hypertension in farmworkers in Yakima, County, WA

  At the time of screening

Interventions

Hemoglobin A1C DIAGNOSTIC_TEST

Finger stick hemoglobin A1C

Urinalysis DIAGNOSTIC_TEST

Urinalysis by dip stick looking for urine protein level

Whole blood creatinine level DIAGNOSTIC_TEST

Finger stick looking for serum creatinine as an estimate of renal function

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All adults of between the ages of 18 and 75 who do not meet the exclusion criteria and wish to undergo screening for kidney disease and diabetes.

You may qualify if:

• Between the ages of 18 and 75

You may not qualify if:

• Active malignancy
• Currently pregnant
• End stage renal disease requiring dialysis
• Current active treatment for diabetes mellitus
• Current care by a nephrologist for chronic kidney disease

Sponsors & Collaborators

• Pacific Northwest University of Health Sciences: lead

Related Publications (7)

• Hebert JR, Braun KL, Kaholokula JK, Armstead CA, Burch JB, Thompson B. Considering the Role of Stress in Populations of High-Risk, Underserved Community Networks Program Centers. Prog Community Health Partnersh. 2015;9 Suppl(0):71-82. doi: 10.1353/cpr.2015.0028.

  PMID: 26213406 BACKGROUND

• Coronado GD, Thompson B, Tejeda S, Godina R, Chen L. Sociodemographic factors and self-management practices related to type 2 diabetes among Hispanics and non-Hispanic whites in a rural setting. J Rural Health. 2007 Winter;23(1):49-54. doi: 10.1111/j.1748-0361.2006.00067.x.

  PMID: 17300478 BACKGROUND

• Ferdinand KC, Weitzman R, Israel M, Lee J, Purkayastha D, Jaimes EA. Efficacy and safety of aliskiren-based dual and triple combination therapies in US minority patients with stage 2 hypertension. J Am Soc Hypertens. 2011 Mar-Apr;5(2):102-13. doi: 10.1016/j.jash.2011.01.006.

  PMID: 21414565 BACKGROUND

• Kurpas D, Mroczek B, Bielska D. Rural and urban disparities in quality of life and health-related behaviors among chronically ill patients. Rural Remote Health. 2014;14(2):2485. Epub 2014 Jun 10.

  PMID: 24916658 BACKGROUND

• Krishna S, Gillespie KN, McBride TM. Diabetes burden and access to preventive care in the rural United States. J Rural Health. 2010 Winter;26(1):3-11. doi: 10.1111/j.1748-0361.2009.00259.x.

  PMID: 20105262 BACKGROUND

• Melvin CL, Corbie-Smith G, Kumanyika SK, Pratt CA, Nelson C, Walker ER, Ammerman A, Ayala GX, Best LG, Cherrington AL, Economos CD, Green LW, Harman J, Hooker SP, Murray DM, Perri MG, Ricketts TC; Workshop Working Group on CVD Prevention in High-Risk Rural Communities. Developing a research agenda for cardiovascular disease prevention in high-risk rural communities. Am J Public Health. 2013 Jun;103(6):1011-21. doi: 10.2105/AJPH.2012.300984. Epub 2013 Apr 18.

  PMID: 23597371 BACKGROUND

• Shoham DA, Vupputuri S, Kaufman JS, Kshirsagar AV, Diez Roux AV, Coresh J, Heiss G. Kidney disease and the cumulative burden of life course socioeconomic conditions: the Atherosclerosis Risk in Communities (ARIC) study. Soc Sci Med. 2008 Oct;67(8):1311-20. doi: 10.1016/j.socscimed.2008.06.007. Epub 2008 Jul 28.

  PMID: 18667261 BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Diabetes Mellitus; Hypertension

Interventions

Urinalysis

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Clinical Chemistry Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Diagnostic Techniques, Urological; Investigative Techniques

Study Officials

• Mark D Baldwin, DO

  Pacific Northwest University of Health Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 4, 2019
• First Posted: June 5, 2019
• Study Start: February 1, 2020
• Primary Completion: February 5, 2020
• Study Completion: February 5, 2020
• Last Updated: July 14, 2022

Record last verified: 2022-07