Clinical and Radiological Evaluation of Acoustic Neuromas With Spontaneous Shrinkage

NCT03970681 | Unknown

• 1 other identifier: 7417
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the regression characteristics of this Acoustic Neuroma population using volumetric data To study the relationship between regression and clinical characteristics including tinnitus, dizziness, hearing loss, and the intrinsic characteristics of the patients.

Conditions

Neuroma, Acoustic

Keywords

Acoustic neuroma; Vestibular schwannoma; Spontaneous shrinkage; Neoplasm regression; Volume quantification; Tridimensional measurements; Volumetric measurements

Outcome Measures

Primary Outcomes (1)

• Measurement of tumoral volume using tridimensional reconstruction on MRI, and kinetics of decay

  Files analyzed from January 01, 2013 to June 30, 2018

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subject followed in radiology for the assessment or follow-up of neuroma between January 01, 2013 and June 30, 2018

You may qualify if:

• Major subject (≥18 years old)
• Subject followed in radiology for the assessment or follow-up of neuroma between January 01, 2013 and June 30, 2018
• Subject who has agreed to the use of his data for the purpose of this research
• Subject presenting an untreated neuroma

You may not qualify if:

• Subject having expressed his opposition to participating in the study
• Subject followed for neuroma of other cranial pairs,
• Subject followed in the context of type II neurofibromatosis
• Subject with a treated neuroma (radiotherapy or surgery)

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service D'Orl Et de Chirurgie Cervico-Faciale

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Neuroma, Acoustic

Condition Hierarchy (Ancestors)

Neurilemmoma; Neuroendocrine Tumors; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms; Neuroma; Nerve Sheath Neoplasms; Neoplasms, Nerve Tissue; Cranial Nerve Neoplasms; Nervous System Neoplasms; Neoplasms by Site; Peripheral Nervous System Neoplasms; Vestibulocochlear Nerve Diseases; Retrocochlear Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Otorhinolaryngologic Neoplasms; Cranial Nerve Diseases; Nervous System Diseases

Central Study Contacts

Anne CHARPIOT, MD, PhD

CONTACT

33 3 88 12 76 49; anne.charpiot@chru-strasbourg.fr

Guillaume TRAU, MD

CONTACT

33 3 88 12 76 49; Guillaume.trau@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 29, 2019
• First Posted: May 31, 2019
• Study Start: May 29, 2019
• Primary Completion: May 1, 2020
• Study Completion: May 1, 2020
• Last Updated: May 31, 2019

Record last verified: 2019-05

Locations

FR (1)