Behavioral Addictions and Related NeuroCOgnitive Aspects

NCT03967418 | Completed

• 1 other identifier: RC19_0177
• Study Type: interventional
• Target: 116
• Locations: 1 country
• Sites: 1

Brief Summary

Improving knowledge about behavioural addictions is a real public health issue. The etiopathogenic model of behavioural addictions is multifactorial, with various risk and vulnerability factors, involved in the initiation and maintenance of the disorders. Among these factors, neurocognitive alterations associated with behavioural addictions has recently aroused interest among researchers. To our knowledge, there is no work wich compared several behavioural addictions with each other on a neurocognitive level. Moreover, neurocognitive data concerning certain behavioural addictions (such as sexual addiction) is almost non-existent. However, understanding the neurocognitive profiles of these patients would allow the investigators, on the one hand, to reinforce the existing literature and improve our understanding of the global process of addiction, and on the other hand, to propose alternative approaches to its management, taking into account the neurocognitive difficulties of the patients. The investigators therefore propose to explore the neurocognitive alterations of patients suffering from several behavioural addiction (sexual addiction and eating disorders with bulimia episodes), by comparing them with each other, to matched healthy control groups and to a recognized behavioural addiction (gambling disorder; data from the BANCO study - NCT03202290).

Conditions

Behavioral Addiction

Keywords

Behavioral addiction; neurocognition; neuropsychology; sexual addiction; eating disorders

Outcome Measures

Primary Outcomes (1)

• Scores obtained at the various neurocognitive tests used

  A composite score will be created to reflect the overall level of cognitive performance of individuals with behavioral addictions, compared to healthy controls

  4 hours

Study Arms (2)

Patients with behavioral addictions

OTHER

Patients suffering from behavioural addiction (sexual addiction and eating disorders with bulimia episodes) will be recruited

Behavioral: Cognitive and clinical assessment

Healthy volunteers

OTHER

Healthy volunteers will be matched on gender, age and education level to patients

Behavioral: Cognitive and clinical assessment

Interventions

Cognitive and clinical assessment BEHAVIORAL

The content of the assessment will be the same for all subjects and will consist of a cognitive assessment (neurocognition, social cognition, metacognition, emotional reactivity) and a clinical assessment (impulsivity, personality, psychiatric and addictive comorbidities)

Healthy volunteers; Patients with behavioral addictions

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• More than 15 years and 3 months old
• Mastering the French language
• Social Security Affiliates
• Having given consent
• Correct level of vision allowing the reading of instructions, the distinction of shapes and colours and the understanding of shapes and images presented in cognitive tasks (subjectively attested by the patient)
• Correct hearing level, allowing a good understanding of the sounds presented (subjectively attested by the patient and the assessor at the first contact for eligibility)
• Suffering from one of the behavioural addiction explored
• Beginning treatment in the Addictology department of the University Hospital of Nantes
• \- Free from the explored behavioural addictions

You may not qualify if:

• Current and not stabilized psychiatric and addictive disorders (mood disorders, anxiety disorders and substance-use disorders except nicotine, lifetime psychotic syndrome), diagnosed by the MINI and after consultation with the clinician,
• Non stabilized endocrine disorders
• Neurological disorders (such as head trauma, neurodegenerative diseases, unbalanced epilepsy, mental retardation, etc.),
• Taking a psychotropic treatment wich is not stabilized for at least 2 weeks,
• Consumption of a psychoactive substance - other than nicotine - within the 12 hours prior to the assessment,
• Color blindness
• Cardiac problems self-reported by the patient, in order to avoid bias in the measurement of cardiac parameters,
• Electrical implants as declared by the participant (to avoid measurement artifacts)
• Having benefited from current or past cognitive remediation program
• Reporting being pregnant or breastfeeding
• Current participation or in the past month in a pharmacological research protocol
• Presenting difficulties for reading or writing French
• Being under guardianship
• With significant cognitive impairment not compatible with de cognitive assessment
• \- Suffering from one of the behavioural addiction explored

Sponsors & Collaborators

• Nantes University Hospital: lead

Study Sites (1)

CHU de Nantes

Nantes, 44093, France

Location

Related Publications (1)

• Hurel E, Grall-Bronnec M, Thiabaud E, Saillard A, Hardouin JB, Challet-Bouju G. A Case-Control Study on Behavioral Addictions and Neurocognition: Description of the BANCO and BANCO2 Protocols. Neuropsychiatr Dis Treat. 2021 Jul 20;17:2369-2386. doi: 10.2147/NDT.S292490. eCollection 2021.

  PMID: 34321880 DERIVED

MeSH Terms

Conditions

Compulsive Sexual Behavior Disorder; Feeding and Eating Disorders

Condition Hierarchy (Ancestors)

Behavior, Addictive; Compulsive Behavior; Impulsive Behavior; Behavior; Sexual and Gender Disorders; Sexual Dysfunctions, Psychological; Mental Disorders; Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Marie GRALL BRONNEC, Pr

  Nantes University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 27, 2019
• First Posted: May 30, 2019
• Study Start: October 28, 2019
• Primary Completion: June 26, 2025
• Study Completion: June 26, 2025
• Last Updated: July 4, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)