Multi-slice CT Coronary Angiography in Patients With Stable Angina
1 other identifier
observational
150
0 countries
N/A
Brief Summary
early identification of vulnerable plaques by remodeling index prior to rupture and development of acute event is of considerable importance especially by a reliable non-invasive method as CT coronary angiography.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2016
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 30, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2018
CompletedFirst Submitted
Initial submission to the registry
May 21, 2019
CompletedFirst Posted
Study publicly available on registry
May 24, 2019
CompletedMay 28, 2019
May 1, 2019
2.1 years
May 21, 2019
May 23, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
remodeling of the coronary artery
to study the changes in wall of the arteries in patients with chronic stable angina early changes don't appear in coronary angiography as it occurs in the form of positive remodeling which can be detected by multisclice coronary angiography Remodeling index is defined as the ratio of the maximum vessel area (or diameter) to a normal reference vessel area (or diameter), and plaques are classified as having significant positive remodeling when the remodeling index is \>1.1
2 years
Interventions
assessment of the remodeling index by multisclice CT in patients with chronic stable angina
Eligibility Criteria
evaluation of coronary artery remodeling index in patients with low to intermediate risk stable angina by MSCT coronary angiography.
You may qualify if:
- first attack, low to intermediate risk stable angina
- normal resting ECG,
- negative markers
- normal systolic function by 2D echocardiography (EF\>50%)
- without regional wall motion abnormality at rest who were referred to MSCT evaluation of the coronary artery tree.
You may not qualify if:
- previous acute coronary syndrome or revascularization, those with renal impairment or dye hypersensitivity, patients with morbid obesity (BMI\>40kg/m²), rhythm other than sinus rhythm inability to hold breath for 10sec to acquire the image lesions with heavy calcium score.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Benha Universitylead
Related Publications (1)
Mostafa SA, Aboelazem T, Sanad O, Abdelghafar H, Azam A. Multi-slice CT coronary angiography assessment of remodeling index in patients with low- to intermediate-risk stable angina. Egypt Heart J. 2019 Sep 11;71(1):7. doi: 10.1186/s43044-019-0011-5.
PMID: 31659543DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- assistant professor
Study Record Dates
First Submitted
May 21, 2019
First Posted
May 24, 2019
Study Start
January 1, 2016
Primary Completion
January 30, 2018
Study Completion
March 1, 2018
Last Updated
May 28, 2019
Record last verified: 2019-05