Iron Deficiency Anemia Among Chinese Pregnant Women: a Multi-center Prospective Cohort Study
IRONWOMEN
1 other identifier
observational
5,551
1 country
7
Brief Summary
Iron deficiency anemia during pregnancy, which may lead to adverse pregnancy outcomes, was a serious health problem in China. Various iron supplements used in different regions of China, however, the effects have not been well investigated. The objective of this study is to investigate the diagnosis, treatment and prognosis of iron deficiency and iron deficiency anemia in Chinese pregnant women.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2019
Typical duration for all trials
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 10, 2019
CompletedFirst Submitted
Initial submission to the registry
May 21, 2019
CompletedFirst Posted
Study publicly available on registry
May 23, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
November 30, 2021
CompletedMay 7, 2024
May 1, 2024
2.4 years
May 21, 2019
May 6, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
adverse maternal outcomes
Including iron deficiency anemia rate, pregnancy hypertension syndrome rate, gestational diabetes mellitus rate, cesarean section rate, and other adverse maternal outcomes rate. The definition of adverse maternal outcome was according to International Glossary on Infertility and Fertility Care (2017), and the rate of adverse maternal outcome was calculated by the number of adverse maternal outcome divided by the total number of pregnant women.
40 weeks
adverse neonatal outcomes
Including miscarriage rate, premature birth rate, birth defect rate, low birth weight rate, and other adverse neonatal outcomes. The definitions of adverse neonatal outcomes were according to International Glossary on Infertility and Fertility Care (2017), and the rate of adverse neonatal outcomes were calculated by the number of advers neonatal outcomes divided by the total number of pregnancy or birth.
40 weeks
Study Arms (2)
Exposure group
Chinese women with iron deficiency anemia (IDA) during pregnancy.
Control group
Chinese women without iron deficiency anemia (IDA) during pregnancy.
Interventions
Iron deficiency anemia exists in Chinese pregnant women during pregnancy
Eligibility Criteria
Chinese pregnant women who established a health record at one of the survey hospital in seven cities of China.
You may qualify if:
- Pregnant women who registered an antenatal care file at the survey hospital ;
- Signed informed consent.
You may not qualify if:
- Participated in any drug or nutritional clinical trial from 3 months before pregnancy to recruitment.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- West China Hospitallead
- West China Second University Hospitalcollaborator
Study Sites (7)
Peking University People's Hospital
Beijing, Beijing Municipality, China
Chongqing Health center for women and Children
Chongqing, Chongqing Municipality, China
Xiamen Maternal and Child Care Hospital
Xiamen, Fujian, China
Hubei Maternal and Child Care Hospital
Wuhan, Hubei, China
Yanan University Affiliated Hospital
Yanan, Shanxi, China
The West China Second University Hospital
Chengdu, Sichuan, 610041, China
Women'S Hospital School of Medicine Zhejiang University
Hangzhou, Zhejiang, China
Related Publications (1)
Haider BA, Olofin I, Wang M, Spiegelman D, Ezzati M, Fawzi WW; Nutrition Impact Model Study Group (anaemia). Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis. BMJ. 2013 Jun 21;346:f3443. doi: 10.1136/bmj.f3443.
PMID: 23794316BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Xin Sun, Doctor
West China Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 40 Weeks
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director
Study Record Dates
First Submitted
May 21, 2019
First Posted
May 23, 2019
Study Start
May 10, 2019
Primary Completion
September 30, 2021
Study Completion
November 30, 2021
Last Updated
May 7, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will not share
Data can be shared with other researchers with the agreement of the Coordinating Committee and the Ethics Committee.