DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL
BNP-PL
1 other identifier
observational
3,000
1 country
1
Brief Summary
The BNP-PL is a multicenter, observational study in which patients are prospectively followed in order to investigate clinical course and management of pulmonary hypertension in Poland. All patients diagnosed with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension confirmed in right heart catheterization, will be eligible to participate in the study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2018
CompletedFirst Submitted
Initial submission to the registry
March 26, 2019
CompletedFirst Posted
Study publicly available on registry
May 22, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 28, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
February 28, 2028
ExpectedMay 22, 2019
May 1, 2019
5 years
March 26, 2019
May 20, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mortality
The number of patients who die during the follow-up period
Since enrollment until at least 5 years.
Study Arms (3)
PAH adults
Patients with pulmonary arterial hypertension who are at least 18 years old at study entry
PAH children
Patients with pulmonary arterial hypertension who are at least 3 months old and are less than 18 years old at study entry
CTEPH
Patients with chronic thromboembolic pulmonary hypertension who are at least 18 years old at study entry
Eligibility Criteria
Patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension treated in Polish centres of pulmonary hypertension accredited by the National Health Fund
You may qualify if:
- Patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension diagnosed after 1st March 2018 (incident cases) who:
- are aged \> 3 months at the time of enrollment
- fulfill the following hemodinamic criteria: mean pulmonary arterial pressure (mPAP) of 25 mm Hg or more, mean pulmonary arterial wedge pressure (PAWP) or left ventricular end-diastolic pressure (PVEDP) of 15 mm Hg or less, pulmonary vascular resistance (PVR) of 3 Woods.
- Patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension diagnosed before 1st March 2018 (prevalent cases) who:
- are aged \> 3 months at the time of enrollment
- fulfill the following hemodinamic criteria: mean pulmonary arterial pressure (mPAP) of 25 mm Hg or more, mean pulmonary arterial wedge pressure (PAWP) or left ventricular end-diastolic pressure (PVEDP) of 15 mm Hg or less, pulmonary vascular resistance (PVR) of 3 Woods
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Polish Cardiology Associationlead
- Jagiellonian Universitycollaborator
Study Sites (1)
Krakowski Szpital Specjalistyczny im. Jana Pawła II
Krakow, 31-202, Poland
Related Publications (2)
Waligora M, Kurzyna M, Mularek-Kubzdela T, Skoczylas I, Chrzanowski L, Blaszczak P, Jaguszewski M, Kusmierczyk B, Ptaszynska K, Grzesk G, Mizia-Stec K, Malinowska E, Peregud-Pogorzelska M, Lewicka E, Tomaszewski M, Jachec W, Florczyk M, Mroczek E, Gasior Z, Pawlak A, Betkier-Lipinska K, Pruszczyk P, Widejko K, Zablocka W, Kopec G. Effects of beta-Blockers on the Outcomes in Patients With Pulmonary Arterial Hypertension Stratified by the Presence of Comorbid Conditions: A Multicenter Prospective Cohort Study: The Database of Pulmonary Hypertension in the Polish Population (BNP-PL). Chest. 2025 Apr;167(4):1171-1181. doi: 10.1016/j.chest.2024.10.051. Epub 2024 Nov 9.
PMID: 39528108DERIVEDKopec G, Dzikowska-Diduch O, Mroczek E, Mularek-Kubzdela T, Chrzanowski L, Skoczylas I, Tomaszewski M, Peregud-Pogorzelska M, Karasek D, Lewicka E, Jachec W, Gasior Z, Blaszczak P, Ptaszynska-Kopczynska K, Mizia-Stec K, Biederman A, Zielinski D, Przybylski R, Kedzierski P, Waligora M, Roik M, Grabka M, Orlowska J, Araszkiewicz A, Banaszkiewicz M, Slawek-Szmyt S, Darocha S, Magon W, Dabrowska-Kugacka A, Stepniewski J, Jonas K, Kaminski K, Kasprzak JD, Podolec P, Pruszczyk P, Torbicki A, Kurzyna M. Characteristics and outcomes of patients with chronic thromboembolic pulmonary hypertension in the era of modern therapeutic approaches: data from the Polish multicenter registry (BNP-PL). Ther Adv Chronic Dis. 2021 Mar 25;12:20406223211002961. doi: 10.1177/20406223211002961. eCollection 2021.
PMID: 33854746DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Grzegorz Kopeć, MD, Phd
Krakowski Szpital Specjalistyczny im. Jana Pawła II
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Target Duration
- 5 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 26, 2019
First Posted
May 22, 2019
Study Start
March 1, 2018
Primary Completion
February 28, 2023
Study Completion (Estimated)
February 28, 2028
Last Updated
May 22, 2019
Record last verified: 2019-05
Data Sharing
- IPD Sharing
- Will not share