Impact of Exposure to Cosmetics on Sensitive Skin

NCT03958968 | Completed

• 1 other identifier: SENSICOS (29BRC18.0078)
• Study Type: observational
• Target: 161
• Locations: 1 country
• Sites: 2

Brief Summary

The concept of sensitive or reactive skin was evoked in 1947 and developed in the 1970s and is now widely recognized. The international pruritus society has proposed an international consensus definition: sensitive skin is defined as a syndrome manifested by the occurrence of unpleasant sensations (tingling, burning, pain, pruritus, tingling) in response to stimuli that normally do not not cause such sensations. The triggering factors can be cosmetics, water, cold, heat, temperature variations, wind ... etc. The physiopathological mechanisms are debated and several hypotheses exist. Sensitive skin can be considered as a decrease of the threshold of cutaneous tolerance. Sensitive skin is linked to abnormalities of the cutaneous nervous system, which becomes hyper-reactive. This hyperreactivity can be modulated by multiple factors. Exposure to cosmetics could be one of the main triggers for sensitive skin, especially for women. This can be explained by the wide use of cosmetics (in France women apply an average of 16 different cosmetics per day), by overconsumption of cosmetics, by exposure to potentially irritating ingredients. Sensitive skin would be less tolerant to the frequent and prolonged use of cosmetics. However, no precise information is available on the actual consumption of cosmetic products in the population with sensitive skin, in particular no data exists concerning the type of products used, the criteria of choice of products, the daily number of products used. and the ingredients contained in these cosmetics

Conditions

Sensitive Skin; Cosmetic Exposure

Outcome Measures

Primary Outcomes (1)

• Comparison of cosmetics use between subjects with and without sensitive skin

  Ingredients contained in the cosmetics, type of products used and frequencies of use between a group of subjects with sensitive skin and a group without sensitive skin

  during the inclusion visit

Eligibility Criteria

• Age: 18 Years - 65 Years
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

150 persons

You may qualify if:

• Women Between 18 and 65 years old -

You may not qualify if:

• Men Less than 18 years old More than 65 years old Skin disease on the face: acne, rosacea, eczema Refusal to participate

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (2)

Laboratory Interaction Neurons Keratinocytes

Brest, France

Location

Laboratory LINK

Brest, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 20, 2019
• First Posted: May 22, 2019
• Study Start: April 9, 2019
• Primary Completion: September 25, 2019
• Study Completion: September 25, 2019
• Last Updated: February 7, 2022

Record last verified: 2021-01

Locations

FR (2)