The Serum Sclerostin Levels in Cholesteatoma Patients
1 other identifier
observational
75
1 country
1
Brief Summary
The aim of this study is to investigate the levels of sclerostin in patients with cholesteatoma. So far, there is no study showing the levels of sclerostin in cholesteatoma. The investigators hope that the results of our study will start new processes that can be used in the clinic.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2019
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 29, 2019
CompletedFirst Submitted
Initial submission to the registry
April 30, 2019
CompletedFirst Posted
Study publicly available on registry
May 17, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 15, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
March 15, 2020
CompletedMay 21, 2019
May 1, 2019
11 months
April 30, 2019
May 17, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
change of the levels of sclerostin in cholesteatoma at 1 month
So far, there is no study showing the levels of sclerostin in cholesteatoma. The investigators hope that the results of our study will initiate new processes that can be used in clinical applications.
1 month
Study Arms (3)
chronic otitis media
patients with chronic otitis media without cholesteatoma
cholesteatoma
patients with chronic otitis media whose cholesteatoma
control
patients scheduled to operation with diagnosis of other causes
Interventions
Blood sample to measure serum sclerostin level
Eligibility Criteria
The experimental group of this study consisted of 75 patients who applied to AIBU Bolu Izzet Baysal Training and Research Hospital Ear Nose Throat Clinic and regularly followed up. A control group of approximately 50 people, which is demographically similar, and patients whose scheduled for operation with other causes.
You may qualify if:
- cholesteatoma chronic otitis media
You may not qualify if:
- Acute infection Malignancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Özgür Mehmet Yis
Bolu, Merkez, 14100, Turkey (Türkiye)
Biospecimen
serum
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor Doctor
Study Record Dates
First Submitted
April 30, 2019
First Posted
May 17, 2019
Study Start
March 29, 2019
Primary Completion
February 15, 2020
Study Completion
March 15, 2020
Last Updated
May 21, 2019
Record last verified: 2019-05
Data Sharing
- IPD Sharing
- Will not share