Temporal Relationship in Recovery of Muscular Pain and Functional Variables in an Experimental Muscular Pain Model in Hamstrings

NCT03942562 | Completed

• 1 other identifier: PI18/208
• Study Type: observational
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

Basal measurements are taken in relation to the study variables. Immediately subjects perform eccentric exercise on right hamstrings to develop delayed onset muscle soreness (DOMS). Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Conditions

Pain, Muscle

Keywords

DOMS; Healthy subjects; Pressure pain thresholds; Active Knee Extension test; Maximal strength; Electromyography; Plantar pressure measurement; Gait analysis

Outcome Measures

Primary Outcomes (1)

• Changes in spatio temporal parameters of gait

  Changes in spatio temporal parameters of gait over a treadmill will be measurement using an optical measurement system consisting of a transmitting and receiving bar (OptoGait System).

  Baseline, 48 hours, 96 hours, 1 week

Secondary Outcomes (7)

• Changes in Pressure Pain Thresholds

  Baseline, 48 hours, 96 hours, 1 week

• Changes in active knee extension test

  Baseline, 48 hours, 96 hours, 1 week

• Changes in knee-flexors maximal isometric muscle strength

  Baseline, 48 hours, 96 hours, 1 week

• Electromyography (EMG) measurement during the tests

  Baseline, 48 hours, 96 hours, 1 week

• Changes in thermography on hamstrings areas

  Baseline, 48 hours, 96 hours, 1 week

Eligibility Criteria

• Age: 18 Years - 45 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Non sedentary healthy men

You may qualify if:

• not sedentary subject (IPAQ scale \> 600 MET)
• healthy subjects, without pain nor injury at the moment

You may not qualify if:

• subjects with acute or chronic pain on every spot of pelvis or lower limbs at the momento or for the last 3 months;
• subjects with history of severe injury in the hamstrings muscles;
• presence of serious illness;
• presence of pathologies in relation to chronic pain (as fibromyalgia, migraine disorders, non specific and chronic lumbar pain);
• not commitment for continuity in the study program;

Sponsors & Collaborators

• Universidad San Jorge: lead

Study Sites (1)

Universidad San Jorge

Villanueva de Gállego, Zaragoza, 50830, Spain

Location

MeSH Terms

Conditions

Myalgia

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Diseases; Nervous System Diseases; Musculoskeletal Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Víctor Doménech, MSc

  Universidad San Jorge

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 7 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2019
• First Posted: May 8, 2019
• Study Start: October 15, 2018
• Primary Completion: August 31, 2019
• Study Completion: August 31, 2019
• Last Updated: November 10, 2020

Record last verified: 2020-11

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)