Long-term Outcomes of Critical Illness Survivors
1 other identifier
observational
200
1 country
2
Brief Summary
The goal of this study is to assess the Long-term Outcomes of Critical Illness Survivors,including physical, psychological, and cognitive sequelae.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2019
Typical duration for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 1, 2019
CompletedFirst Posted
Study publicly available on registry
May 7, 2019
CompletedStudy Start
First participant enrolled
June 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2021
CompletedJanuary 7, 2020
January 1, 2020
1.3 years
May 1, 2019
January 5, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Survival rate of ICU survivors
Critically ill patients discharged from ICU are defined as survivors
3 or 6 months after ICU discharge
Secondary Outcomes (7)
Assessment of life quality
3 or 6 months after ICU discharge
Assessment in Physical dysfunction
3 or 6 months after ICU discharge
Assessment in depression and anxiety
3 or 6 months after ICU discharge
Assessment in PTSD
3 or 6 months after ICU discharge
Assessment in Cognitive impairments
3 or 6 months after ICU discharge
- +2 more secondary outcomes
Study Arms (1)
Critical Illness Survivors
Those intensive care unit(ICU) patients who survive from critical illness.
Eligibility Criteria
ICU patients of Jiangyin people's hospital
You may qualify if:
- Patients aged \>17 years
- Patients in intensive care unit(ICU) with at least one organ or system dysfunction,such as respiratory failure, cardiogenic shock,or septic shock.
You may not qualify if:
- Refuse to participate
- Death before ICU discharge
- pre-existing cognitive impairment, malignant tumor
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Jian-jun Yanglead
Study Sites (2)
Jiangyin People's Hospital
Jiangyin, Jiangsu, 210009, China
Zhongda Hospital
Nanjing, Jiangsu, 210009, China
Related Publications (3)
Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW; BRAIN-ICU Study Investigators. Long-term cognitive impairment after critical illness. N Engl J Med. 2013 Oct 3;369(14):1306-16. doi: 10.1056/NEJMoa1301372.
PMID: 24088092BACKGROUNDWischmeyer PE, San-Millan I. Winning the war against ICU-acquired weakness: new innovations in nutrition and exercise physiology. Crit Care. 2015;19 Suppl 3(Suppl 3):S6. doi: 10.1186/cc14724. Epub 2015 Dec 18.
PMID: 26728966BACKGROUNDMcNelly AS, Rawal J, Shrikrishna D, Hopkinson NS, Moxham J, Harridge SD, Hart N, Montgomery HE, Puthucheary ZA. An Exploratory Study of Long-Term Outcome Measures in Critical Illness Survivors: Construct Validity of Physical Activity, Frailty, and Health-Related Quality of Life Measures. Crit Care Med. 2016 Jun;44(6):e362-9. doi: 10.1097/CCM.0000000000001645.
PMID: 26974547BACKGROUND
Study Officials
- PRINCIPAL INVESTIGATOR
Jian-jun Yang, PhD
Zhongda Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Director,Department of Anesthesiology
Study Record Dates
First Submitted
May 1, 2019
First Posted
May 7, 2019
Study Start
June 1, 2019
Primary Completion
October 1, 2020
Study Completion
June 30, 2021
Last Updated
January 7, 2020
Record last verified: 2020-01