NCT03940573

Brief Summary

A prospective, open label post-market registry to collect Patient Reported Outcomes and Fitting metrics (e.g. sizes used) in subjects using the Eclipse System in a commercial setting.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2019

Typical duration for not_applicable

Geographic Reach
1 country

6 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 19, 2019

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

May 2, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 7, 2019

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

March 11, 2021

Status Verified

March 1, 2021

Enrollment Period

2.7 years

First QC Date

May 2, 2019

Last Update Submit

March 9, 2021

Conditions

Outcome Measures

Primary Outcomes (4)

  • Fit Rate

    Proportion of patients successfully fit

    Data collected at fitting visits (max 3 attempts), 5-7 weeks from initial screening

  • Device Size Distribution

    Size distribution of devices among successfully fit patients

    Data collected at fitting visits (max 3 attempts), 5-7 weeks from initial screening

  • St. Mark's Score (Vaizey)

    Change from baseline in mean scores (scored 0-24 with 0 = total continence and 24 = total incontinence)

    12 months

  • PGI-I Score

    Patient global impression of improvement score (7 point scale comparing current condition to baseline, from 1 = very much better to 7 = very much worse)

    12 months

Secondary Outcomes (6)

  • St. Mark's Score (Vaizey)

    3 months

  • St. Mark's Score (Vaizey)

    6 months

  • St. Mark's Score (Vaizey)

    9 months

  • PGI-I Score

    3 months

  • PGI-I Score

    6 months

  • +1 more secondary outcomes

Study Arms (1)

Treatment

EXPERIMENTAL

All patients fitted with the device.

Device: Eclipse Insert

Interventions

Rectal Control System.

Treatment

Eligibility Criteria

Age19 Years+
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsFemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult female
  • Diagnosis of Fecal Incontinence
  • Clinician recommendation of the Eclipse System
  • Subject provides informed consent and HIPAA authorization

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

The American Association of Female Pelvic Medicine

Agoura Hills, California, 91301, United States

RECRUITING

The Ob-Gyn and Incontinence Center

Arcadia, California, 91006, United States

RECRUITING

Long Beach Urogynecology

Long Beach, California, 90806, United States

RECRUITING

Florida Urogynecology, LLC

Jacksonville, Florida, 32216, United States

RECRUITING

Mayo Clinic Jacksonville

Jacksonville, Florida, 32224, United States

NOT YET RECRUITING

Princeton Urogynecology

Princeton, New Jersey, 08540, United States

RECRUITING

Related Links

MeSH Terms

Conditions

Fecal Incontinence

Condition Hierarchy (Ancestors)

Rectal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Study Officials

  • Paul Pettit, MD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Steve Herbowy

CONTACT

Jared Goor, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 2, 2019

First Posted

May 7, 2019

Study Start

April 19, 2019

Primary Completion

December 31, 2021

Study Completion

December 31, 2021

Last Updated

March 11, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations