Pilot Study of Annie Text Messaging for Depression Treatment Adherence
Pilot Study of Technology Assisted Depression Treatment Adherence
1 other identifier
interventional
53
1 country
1
Brief Summary
Patients and providers need effective tools to help promote adherence to newly prescribed medications for depression and to determine if this medication is improving depressed mood. This study will test an intervention that uses 1) VA's text messaging program called Annie to help patient's engage in self-management when starting a new medication for depression and 2) My HealtheVet, VA's patient portal, for education and communication with their VA health care team. The goals of this intervention are to improve adherence to depression medication and depressive symptoms in Veterans.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable depression
Started Jun 2019
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 16, 2019
CompletedFirst Posted
Study publicly available on registry
April 29, 2019
CompletedStudy Start
First participant enrolled
June 21, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2020
CompletedResults Posted
Study results publicly available
February 18, 2022
CompletedJuly 27, 2023
July 1, 2023
12 months
April 16, 2019
September 28, 2021
July 19, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Medication Adherence at Baseline, 6 Weeks and 12 Weeks
Medication Adherence Rating Scale - 10 item self-report measure of medication taking attitudes, behaviors, and side effects. It is scored on a 0-10 scale with higher scores indicating greater adherence.
Baseline, 6 and 12 weeks
Secondary Outcomes (2)
Depressive Symptoms at Baseline, 6 Weeks and 12 Weeks
Baseline, 6 and 12 weeks
Medication Side Effects at Baseline, 6 Weeks, and 12 Weeks
Baseline, 6 and 12 weeks
Study Arms (3)
AIMS Intervention
EXPERIMENTALParticipants randomized to the AIMS arm be enrolled in VA's Annie text messaging program and receive the study protocol.
No Intervention
NO INTERVENTIONParticipants randomized to the no intervention arm will not be enrolled in the Annie text messaging program.
AIMS Intervention Plus
EXPERIMENTALParticipants randomized to the AIMS Intervention Plus arm will be enrolled in VA's Annie text messaging program/study protocol and receive a weekly phone call.
Interventions
Participants randomized to the AIMS arm be enrolled in VA's Annie text messaging program and receive the study protocol. Annie text messages will ask the participate to provide feedback about specific domains related to their depression treatment and goals. The Veteran participant will receive a weekly report about their Annie responses through My HealtheVet, VA's patient portal, and instructed to share information with their care team at their next scheduled appointment. In addition, a summary of response will be provided to the participant's clinician prior to their appointment(s) during the studies 12 week time frame.
Participants randomized to the AIMS Plus arm will receive a weekly phone call in addition to being enrolled in VA's Annie text messaging program/study protocol. Annie text messages will ask the participate to provide feedback about specific domains related to their depression treatment and goals. The Veteran participant will receive a weekly report about their Annie responses through My HealtheVet, VA's patient portal, and instructed to share information with their care team at their next scheduled appointment. In addition, a summary of response will be provided to the participant's clinician prior to their appointment(s) during the studies 12 week time frame.
Eligibility Criteria
You may qualify if:
- VA Patient
- Diagnosed with depression
- Initiating or changing to a new antidepressant medication
- Cell phone with text messaging capabilities
- Registered with My HealtheVet
- Follow-up appointment with their provider in the next 12 weeks
- Internet access
- English speaking VA Providers: provide care to a study participant
You may not qualify if:
- Lack of cell phone access/willingness to receive text messages
- Diagnosis of cognitive disorders, psychotic disorders, bipolar disorder, or active substance abuse.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Iowa City VA Health Care System, Iowa City, IA
Iowa City, Iowa, 52246-2292, United States
Related Publications (2)
Turvey C, Fuhrmeister L, Klein D, McCoy K, Moeckli J, Stewart Steffensmeier KR, Suiter N, Van Tiem J. Secure Messaging Intervention in Patients Starting New Antidepressant to Promote Adherence: Pilot Randomized Controlled Trial. JMIR Form Res. 2023 Dec 8;7:e51277. doi: 10.2196/51277.
PMID: 38064267DERIVEDVan Tiem J, Moeckli J, Suiter N, Fuhrmeister L, Pham K, Dindo L, Turvey C. "A link to the outside:" Patient perspectives on a mobile texting program to improve depression self-management. Patient Educ Couns. 2021 Sep;104(9):2154-2158. doi: 10.1016/j.pec.2021.02.018. Epub 2021 Feb 11.
PMID: 33627234DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Carolyn Turvey, Ph.D.
- Organization
- Department of Veterans Affairs
Study Officials
- PRINCIPAL INVESTIGATOR
Carolyn L Turvey, PhD MS
Iowa City VA Health Care System, Iowa City, IA
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- FED
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 16, 2019
First Posted
April 29, 2019
Study Start
June 21, 2019
Primary Completion
May 31, 2020
Study Completion
June 30, 2020
Last Updated
July 27, 2023
Results First Posted
February 18, 2022
Record last verified: 2023-07
Data Sharing
- IPD Sharing
- Will not share
Original VA funded datasets will be retained on VA servers behind VA firewalls. These data will be provided to interested parties following proper filing and verification of a FOIA request and approval by the Privacy Officer. These data will be maintained as required by VA data retention policies.