Acute Presentation and Management of Abdominal Tuberculosis: A Ten-year Experience at a Tertiary Care Center in Pakistan
1 other identifier
interventional
80
1 country
1
Brief Summary
A prospective interventional study was conducted in Services Instituton of Medical Sciences all patients who underwent emergency laparotomy from 2008-2018 due to abdominal tuberculosis. Data were analyzed using SPSS version 21
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2008
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
April 30, 2018
CompletedFirst Submitted
Initial submission to the registry
April 15, 2019
CompletedFirst Posted
Study publicly available on registry
April 17, 2019
CompletedApril 17, 2019
April 1, 2019
10 years
April 15, 2019
April 15, 2019
Conditions
Outcome Measures
Primary Outcomes (3)
Percentage of patients who develop complications after surgery
Complications of surgery like leakage of gut content, enterocutaneous fistula, intestinal obstruction
9 months
Percentage of patients who develop recurrence of abdominal tuberculosis (elevated ESR, CT scan findings of abdominal tuberculosis)
Recurrence of abdominal tuberclosis assessed by ESR, CT scan Abdomen, Biopsy
1 year
Mortality rate
death due to postoperative complications
9 months
Study Arms (1)
Exploratory Laparotomy
OTHERExploratory Laparotomy of patients presenting acute abdomen and whose diagnosis later on confirmed on histopathology to be tuberculosis
Interventions
Patients presenting with acute abdomen were operated. Exploratory Laparotomy of patients was done. Further procedure was done according to peroperative findings. Ileostomy for perforation of gut, stricturoplasty for strictutre, biopsy for mesentric lymphadenopathy
Eligibility Criteria
You may qualify if:
- Both sexes and age between years and 90 years
- Patients presenting with acute abdomen and who underwent exploratory laparotomy
- Patients who diagnosis confirmed on biopsy (caseating granulomas)
You may not qualify if:
- Peritoneal tuberculosis
- Other causes of acute abdomen (Typhoid perforation)
- Patients diagnosed with abdominal tuberculosis and on conservative management
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Services hospital
Lahore, Punjab Province, 54000, Pakistan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Mahmmood Ayyaz, mbbs, fcps
Services Hospital, Lahore
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principle investigator
Study Record Dates
First Submitted
April 15, 2019
First Posted
April 17, 2019
Study Start
May 1, 2008
Primary Completion
April 30, 2018
Study Completion
April 30, 2018
Last Updated
April 17, 2019
Record last verified: 2019-04