Selective Criteria and a Modified Technique of Applying "URAGPI" Technique for More Proximal Degree of Hypospadias

NCT03911635 | Unknown

• 1 other identifier: URAGPI in hypospadias
• Study Type: interventional
• Target: 75
• Locations: 0 countries
• Sites: N/A

Brief Summary

Hypospadias is a condition in which the location of the urethral meatus is on the ventral aspect of the penis. Hypospadias is the most common congenital anomaly of urogenital organs in boys, with an incidence of approximately 1 in 250 newborns. Recently, case selection has been advised to avoid possible complications and limitations \[1\]. The meatal advancement and glanuloplasty (MAGPI) procedure was first described in 1981 for the repair of distal hypospadias. An excellent surgical result requires careful case selection, avoiding cases with thin or rigid ventral para-meatal skin or a meatus too proximal or too wide. The glans wrap to support the advanced ventral urethral wall requires a solid tissue approximation in two layers to prevent regression of the meatus. Meatal stenosis can be avoided by assuring an adequate dorsal Heineke- Mikulicz tissue rearrangement and making an incision from within the urethral meatus well distally into the urethral groove. . The overall success rate with the MAGPI procedure suggests that it should continue to be used in the repair of distal hypospadias \[2\]. The advantage of Urethral advancement, Glanuloplasty, and Preputioplasty \" URAGPI\" versus MAGPI Is that A) Applicability to almost any type of distal hypospadias regardless of the severity of glanular ventriflexion. B) Normal appearance of the penis. C) Good functional results.

Conditions

Hypospadias

Outcome Measures

Primary Outcomes (1)

• Assessment of the patient immediately after removal of the catheter at the 7th day and after 3 weeks

  evaluation according to "Hypospadias Objective Penile Evaluation Score"

  3 weeks

Study Arms (1)

Hypospadias in children

EXPERIMENTAL

Distal shaft hypospadias at age of 12 years or less

Procedure: URAGPI technique

Interventions

URAGPI technique PROCEDURE

the Urethral Advancement, Glanuloplasty and Preputioplasty

Hypospadias in children

Eligibility Criteria

• Age: 1 Year - 12 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• All patient with hypospadias from 1 to 12 years with penile selection according to Wang YN et. al

You may not qualify if:

• circumcised patients
• sever degrees of chordae
• previous surgical repair
• meatal stenosis

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Hypospadias

Condition Hierarchy (Ancestors)

Urogenital Abnormalities; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Penile Diseases; Genital Diseases, Male; Genital Diseases; Male Urogenital Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 23, 2019
• First Posted: April 11, 2019
• Study Start: April 1, 2020
• Primary Completion: January 1, 2021
• Study Completion: March 1, 2021
• Last Updated: January 9, 2020

Record last verified: 2020-01