Prevalence of Sarcopenia Among Elderly Living in Care Facilities in Klang Valley, Malaysia

NCT03903328 | Completed

• 1 other identifier: U/SERC/77/2016
• Study Type: observational
• Target: 205
• Locations: 0 countries
• Sites: N/A

Brief Summary

The primary aim of this study was to investigate the prevalence of age-related progressive decline in muscle mass and strength (Sarcopenia) among Malaysian elderly residing in long-term care facilities. It is a very important condition to study as it is associated with high incidence of fall, hospitalization and mortality.

Conditions

Sarcopenia; Sarcopenic Obesity

Keywords

muscle strength; physical performance; Sarcopenia

Outcome Measures

Primary Outcomes (3)

• Skeletal muscle mass

  The skeletal muscle mass was measured using a Research grade Segmental BioImpedance Analyser to help derive the skeletal muscle mass index (Appendicular skeletal muscle mass/square of height= kg/m2)

  10 minutes

• Grip strength

  Measurement of muscle strength was done using a Jamar hydraulic handheld dynamometer, only one maximal effort was allowed. However, for erroneous performance another attempt was provided after 10 minutes of rest. The measure was recorded in Kgf.

  1 minute to 10 minutes

• Gait speed

  Usual gait speed was used as a measure of physical performance, where the subject was required to walk along a 5 meter straight path. Time recorded using a stopwatch and speed recorded in meters per second

  less the 10 minutes on an average

Interventions

Sarcopenia assessment OTHER

Sarcopenia assessment by measurement of Skeletal Muscle mass index, hand grip strength and usual gait speed for 5 meter distance, as per the guidelines of Asia Working group for Sarcopenia study, was carried out.

Also known as: Height and weight measurements, Skeletal muscle mass index, Hand grip strength, Gait speed

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Elderly living in long-term care facilities (Institutionalized elderly) in Klang valley. Only Seven facilities allowing access to the study subjects were studied

You may qualify if:

• Currently residing in a long-term care facility
• Ability to walk, with or without the use of any walking aid
• Citizen of Malaysia

You may not qualify if:

• Inability to stand for height, weight and gait speed assessments
• Presence of cardiac pacemaker
• Presence of artificial limbs / prosthesis / metal implants
• Difficult or dangerous behaviours
• Severe cardiac, pulmonary, or musculoskeletal disorders
• Severe cognitive impairment or any disability that makes communication impossible
• Presence of terminal illness
• Co-morbidities associated with high risk of falls (e.g. Parkinson's disease or CVA) or that may directly influence affect gait speed

Sponsors & Collaborators

• Universiti Tunku Abdul Rahman: lead

Related Publications (6)

• Abizanda P, Navarro JL, Garcia-Tomas MI, Lopez-Jimenez E, Martinez-Sanchez E, Paterna G. Validity and usefulness of hand-held dynamometry for measuring muscle strength in community-dwelling older persons. Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):21-7. doi: 10.1016/j.archger.2011.02.006. Epub 2011 Mar 2.

  PMID: 21371760 BACKGROUND

• Abridged Life Tables, Malaysia, 2012-2015. (2015). Department of Statistics Malaysia. Retrieved from: https://www.statistics.gov.my/index.php?r=column/pdfPrev&id=cWxzRWcvMTZrWFp4UStqQmp3MG9QZz09

  BACKGROUND

• Arai H, Akishita M, Chen LK. Growing research on sarcopenia in Asia. Geriatr Gerontol Int. 2014 Feb;14 Suppl 1:1-7. doi: 10.1111/ggi.12236. No abstract available.

  PMID: 24450555 BACKGROUND

• Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, Chou MY, Chen LY, Hsu PS, Krairit O, Lee JS, Lee WJ, Lee Y, Liang CK, Limpawattana P, Lin CS, Peng LN, Satake S, Suzuki T, Won CW, Wu CH, Wu SN, Zhang T, Zeng P, Akishita M, Arai H. Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc. 2014 Feb;15(2):95-101. doi: 10.1016/j.jamda.2013.11.025.

  PMID: 24461239 BACKGROUND

• Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010 Jul;39(4):412-23. doi: 10.1093/ageing/afq034. Epub 2010 Apr 13.

  PMID: 20392703 BACKGROUND

• Cruz-Jentoft AJ, Landi F, Schneider SM, Zuniga C, Arai H, Boirie Y, Chen LK, Fielding RA, Martin FC, Michel JP, Sieber C, Stout JR, Studenski SA, Vellas B, Woo J, Zamboni M, Cederholm T. Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing. 2014 Nov;43(6):748-59. doi: 10.1093/ageing/afu115. Epub 2014 Sep 21.

  PMID: 25241753 BACKGROUND

MeSH Terms

Conditions

Sarcopenia

Interventions

Body Height; Hand Strength; Walking Speed

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Body Size; Body Weights and Measures; Body Constitution; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis; Physical Appearance, Body; Anthropometry; Investigative Techniques; Physiological Phenomena; Growth; Growth and Development; Muscle Strength; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Gait; Walking; Locomotion; Movement

Study Officials

• PRAMOD D SHENOY, MPT

  Universiti Tunku Abdul Rahman

  PRINCIPAL INVESTIGATOR

• sook Fan Yap, FRCP (UK)

  Universiti Tunku Abdul Rahman

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Department of Physiotherapy and Senior Lecturer

Study Record Dates

• First Submitted: April 2, 2019
• First Posted: April 4, 2019
• Study Start: December 6, 2016
• Primary Completion: December 4, 2017
• Study Completion: December 4, 2017
• Last Updated: April 4, 2019

Record last verified: 2019-04

Data Sharing

• IPD Sharing: Will not share