Herpes Zoster: Risk Factors, Complications and Special Situations
1 other identifier
observational
355
1 country
1
Brief Summary
This retrospective analysis is to investigate patients' history and clinical presentation in Herpes Zoster (HZ), Zoster-related complications, post-Zoster neuralgia and Herpes Zoster management in order to improve the management of HZ patients, to refine HZ-vaccination strategies and elucidate cost factors of HZ in in the setting of a university hospital in Switzerland generally and in a dermatology department specifically.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2018
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 20, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 28, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
February 28, 2019
CompletedFirst Submitted
Initial submission to the registry
April 2, 2019
CompletedFirst Posted
Study publicly available on registry
April 4, 2019
CompletedApril 4, 2019
April 1, 2019
2 months
April 2, 2019
April 3, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
Evaluation of patients' history
Free text evaluation of patients' history (age, sex, comorbidities, immunosuppression, obesity, human immune deficiency Virus (HIV), profession, current medication, vaccinations, seasonal occurence of HZ, history of Varicella Zoster virus (VZV) infection
single time point assessment at baseline
Description of the clinical presentation of HZ
Free text description of the clinical presentation of HZ (localisation, dermatomes affected), Zoster-related acute pain
single time point assessment at baseline
Evaluation of zoster-related complications
Free text evaluation of zoster-related complications (ophthalmic zoster, generalised HZ, Ramsay-Hunt syndrome, zoster meningoencephalitis)
single time point assessment at baseline
Evaluation of the herpes zoster management
Free text evaluation of the herpes zoster management (local (antiviral) treatment, systemic antiviral and other treatments, number of revisits, average treatment-related costs, hospitalisations (rate, duration)
single time point assessment at baseline
Assessment of post-zoster neuralgia
Free text assessment of post-zoster neuralgia (annual incidence, treatment options used)
single time point assessment at baseline
Evaluation of zoster and pregnancy
Free text evaluation of zoster and pregnancy (incidence, time of pregnancy, pregnancy outcomes and complications)
single time point assessment at baseline
Interventions
retrospective report review of HZ patients treated between 2005 and 2018 in the Department of Dermatology at the University Hospital Basel
Eligibility Criteria
patients with HZ who were seen at University Hospital Basel between 2004-2018
You may qualify if:
- Reports of patients with HZ at University Hospital Basel between 2004-2018
You may not qualify if:
- rejection to use patient data
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Dermatology, University Hospital Basel
Basel, 4031, Switzerland
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Simon Müller, Dr. med
Department of Dermatology, University Hospital Basel
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 2, 2019
First Posted
April 4, 2019
Study Start
December 20, 2018
Primary Completion
February 28, 2019
Study Completion
February 28, 2019
Last Updated
April 4, 2019
Record last verified: 2019-04