Multi-elemental Imaging of Lung Tissues With LIBS (Laser-induced Breakdown Spectroscopy)
MEDICO-LIBS
2 other identifiers
observational
86
1 country
4
Brief Summary
Evaluate the feasibility of performing a multi-elemental imaging analysis of lung specimens from patients with ILDs, with an technology named LIBS (Laser Induced-Breakdown Spectroscopy)
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2020
Longer than P75 for all trials
4 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 28, 2019
CompletedFirst Posted
Study publicly available on registry
April 3, 2019
CompletedStudy Start
First participant enrolled
January 22, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 9, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
April 9, 2024
CompletedAugust 30, 2024
August 1, 2024
4.2 years
March 28, 2019
August 29, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Generation of multi-elemental images in tissues with LIBS
Evaluation of the feasibility of collecting and describing LIBS multi-elemental images of lung specimens originating from patients with ILDs
Within a month after reception of the biopsy by the analytical laboratory
Secondary Outcomes (3)
Description of elemental distribution in the specimens
Within a month after reception of the biopsy by the analytical laboratory
Interpretation of the elemental maps
Within a month after reception of the biopsy by the analytical laboratory
Comparison of the elemental distributions with results of other mineralogical investigations
Within a month after reception of the biopsy by the analytical laboratory
Study Arms (1)
Interstitial Lung Disease
Ex : sarcoidosis, IPF
Interventions
LIBS multi elemental analysis of the specimen
Eligibility Criteria
Adults with Interstitial Lung Disease
You may qualify if:
- Patient with ILD
- Patient informed, and agreed to participate
You may not qualify if:
- Patient opposed to participating in the study.
- Patient without available specimen.
- Patient under legal protection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (4)
Grenoble Alpes University Hospital
Grenoble, 38043, France
CHRU de LILLE
Lille, 59000, France
CHU de Lyon HCL - GH Sud
Lyon, 69310, France
Hôpital Louis Pradel
Lyon, 69677, France
Related Publications (2)
Busser B, Moncayo S, Trichard F, Bonneterre V, Pinel N, Pelascini F, Dugourd P, Coll JL, D'Incan M, Charles J, Motto-Ros V, Sancey L. Characterization of foreign materials in paraffin-embedded pathological specimens using in situ multi-elemental imaging with laser spectroscopy. Mod Pathol. 2018 Mar;31(3):378-384. doi: 10.1038/modpathol.2017.152. Epub 2017 Nov 17.
PMID: 29148536RESULTBusser et al., Coord Chem Rev, 2018, 358, p70
RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Benoit Busser, PharmD, PhD
Grenoble Alpes University Hospital
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 28, 2019
First Posted
April 3, 2019
Study Start
January 22, 2020
Primary Completion
April 9, 2024
Study Completion
April 9, 2024
Last Updated
August 30, 2024
Record last verified: 2024-08
Data Sharing
- IPD Sharing
- Will not share