NCT03900650

Brief Summary

Although correct, consistent condom use can greatly reduce sexually transmitted infections and unplanned pregnancies, resistance of condom use is common among young adults. Young men's alcohol intoxication and sexual aggression history are predictive of greater condom use resistance and other sexual risk behaviors (e.g., unprotected sex). Moreover, emotional factors may play a role in these associations, suggesting a promising avenue for continued research. This project builds upon our prior research through investigation of the emotional mechanisms involved in young men's alcohol-related sexual risk behavior. This research addresses a critical knowledge gap and advances the field through the use of multiple methods designed to evaluate distal and proximal emotional factors implicated in alcohol-related sexual risk. Male drinkers aged 21-30 who use condoms inconsistently (N = 420) will first complete a screening procedure followed by a baseline survey that will assess relevant constructs, including emotional traits, emotion dysregulation tendencies, and alcohol expectancies. They will then complete a 30-day daily diary assessment of their daily emotional states, daily coping motives pertaining to drinking and sex, and daily drinking and sexual risk behaviors to evaluate daily relationships among these factors. The same participants will complete an in-lab experiment assessing in-the-moment effects of alcohol intoxication and provocation on emotional states and sexual risk intentions. Statistical analyses will be used to examine the daily influence of emotional states and coping motives on alcohol consumption and sexual risk behaviors and the experimental effects of alcohol intoxication and provocation on emotional states and other mediators, as well as sexual risk intentions. Moderating effects of emotion dysregulation tendencies will also be examined, and the linkages between event-level and experimental relationships will be investigated. This research is both significant and innovative in that it will address the public health concern of men's sexual risk behaviors, including condom use resistance; will evaluate the role of emotional processes in men's alcohol-related sexual risk; and will use multiple methods to gather complementary types of data that will elucidate the mechanisms underlying alcohol-related sexual risk behaviors and provide an empirical evidence base from which to develop and inform prevention and intervention programs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
420

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 7, 2019

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

March 28, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 3, 2019

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 5, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 5, 2023

Completed
5 months until next milestone

Results Posted

Study results publicly available

November 29, 2023

Completed
Last Updated

November 29, 2023

Status Verified

November 1, 2023

Enrollment Period

4.3 years

First QC Date

March 28, 2019

Results QC Date

October 3, 2023

Last Update Submit

November 8, 2023

Conditions

Keywords

Condom use resistanceEmotion dysregulation

Outcome Measures

Primary Outcomes (2)

  • Mean Score of Sexual Risk Intentions

    Scale name: Intentions to have unprotected sex Construct: Self-reported ratings of unprotected sex likelihood in a hypothetical scenario Scale range: 1 (not at all likely) to 7 (very likely) A higher value is a worse outcome. This is one total scale (no subscales). Items are averaged to compute a mean score.

    within one hour of receiving the intervention

  • Sexual Risk Behavior

    Number of unprotected sexual intercourse events

    30 days

Study Arms (4)

Alcoholic beverage, High Provocation Manipulation

EXPERIMENTAL

Participants will receive a dose of alcohol mixed in fruit juice designed to achieve a peak breath alcohol concentration of .08%. Participants then receive an experimental manipulation designed to evoke negative emotions such as frustration.

Behavioral: High provocation manipulationBehavioral: Alcoholic beverage

Non-alcoholic beverage, High Provocation Manipulation

EXPERIMENTAL

Participants will receive a beverage that does not contain alcohol (fruit juice only). Participants then receive an experimental manipulation designed to evoke negative emotions such as frustration.

Behavioral: High provocation manipulationBehavioral: Non-alcoholic beverage

Alcoholic beverage, Low provocation manipulation

EXPERIMENTAL

Participants will receive a dose of alcohol mixed in fruit juice designed to achieve a peak breath alcohol concentration of .08%. Participants receive an experimental manipulation designed to evoke positive emotions.

Behavioral: Low provocation manipulationBehavioral: Alcoholic beverage

Non-alcoholic beverage, Low provocation manipulation

EXPERIMENTAL

Participants will receive a beverage that does not contain alcohol (fruit juice only). Participants then receive an experimental manipulation designed to evoke positive emotions.

Behavioral: Low provocation manipulationBehavioral: Non-alcoholic beverage

Interventions

Participants will engage in a laboratory task and will then report their emotions following the task.

Alcoholic beverage, High Provocation ManipulationNon-alcoholic beverage, High Provocation Manipulation

Participants will engage in a laboratory task and will then report their emotions following the task.

Alcoholic beverage, Low provocation manipulationNon-alcoholic beverage, Low provocation manipulation

Participants will consume an alcoholic beverage (vodka mixed with fruit juice) that is the equivalent of 3-4 standard alcoholic drinks based on their body weight.

Alcoholic beverage, High Provocation ManipulationAlcoholic beverage, Low provocation manipulation

Participants will consume a nonalcoholic beverage (fruit juice) that is the isovolemic equivalent of 3-4 standard alcoholic drinks based on their body weight.

Non-alcoholic beverage, High Provocation ManipulationNon-alcoholic beverage, Low provocation manipulation

Eligibility Criteria

Age21 Years - 30 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsSelf-defined as male
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Single
  • Male
  • Ages 21-30
  • Engagement in unprotected intercourse with a woman at least once in the past year -
  • Consumed alcohol at least 2 times per week in the past 30 days
  • Had sex with a woman at least 2 times in the past 30 days

You may not qualify if:

  • A history of alcohol problems
  • A medical condition and/or medications which contraindicate alcohol consumption
  • In a relationship that is monogamous and has lasted longer than 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Arizona State University

Phoenix, Arizona, 85004, United States

Location

MeSH Terms

Conditions

Sexual BehaviorAlcohol Drinking

Interventions

Alcoholic Beverages

Condition Hierarchy (Ancestors)

BehaviorDrinking Behavior

Intervention Hierarchy (Ancestors)

BeveragesDiet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Limitations and Caveats

Data collection was paused for approximately 11 months due to COVID-19 safety protocols.

Results Point of Contact

Title
Kelly Cue Davis
Organization
Arizona State University

Study Officials

  • Kelly Davis, PhD

    Arizona State University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 28, 2019

First Posted

April 3, 2019

Study Start

March 7, 2019

Primary Completion

July 5, 2023

Study Completion

July 5, 2023

Last Updated

November 29, 2023

Results First Posted

November 29, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will share

We will make available individual, de-identified participant data that underlie disseminated results.

Shared Documents
SAP
Time Frame
Immediately following publication and ending 3 years following publication.
Access Criteria
Researchers who provide a methodologically sound proposal for the use of the data.

Locations