NCT03888300

Brief Summary

The study is experimental and aims to (a) compare the viscoelastic properties of bronchial secretions obtained in patients suffering from obstructive respiratory disease, and (b) to compare the viscoelastic properties of bronchial secretions obtained in patients before and after application of a respiratory physiotherapy or exercise as usually prescribed. After agreement, the sputum of the participants will be collected according to the method used in clinical routine.Experiments (collection and analysis of sputum) will be conducted at the Saint-Luc University Clinic.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for not_applicable

Timeline
15mo left

Started Aug 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress85%
Aug 2019Aug 2027

First Submitted

Initial submission to the registry

March 20, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 25, 2019

Completed
4 months until next milestone

Study Start

First participant enrolled

August 1, 2019

Completed
8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

April 29, 2026

Status Verified

April 1, 2026

Enrollment Period

8 years

First QC Date

March 20, 2019

Last Update Submit

April 24, 2026

Conditions

Obstructive Pulmonary Disease

Outcome Measures

Primary Outcomes (1)

  • Viscoelasticity

    Evolution of elastic modulus, viscous modulus, phase angle and non-linear characteristics of lung secretions.

    30 minutes

Study Arms (1)

Patient Group

EXPERIMENTAL

Patients with obstructive pulmonary diseases receiving standard physiotherapy treatment

Other: Physiotherapy

Interventions

PhysiotherapyOTHER

Chest Physiotherapy, physical exercises

Patient Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • obstructive pulmonary disease

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cliniques universitaires Saint-Luc

Brussels, 1200, Belgium

RECRUITING

MeSH Terms

Conditions

Lung Diseases, Obstructive

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

TherapeuticsRehabilitation

Study Officials

  • Gregory Reychler, PT, PhD

    Cliniques universitaires Saint-Luc- Université Catholique de Louvain

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gregory Reychler, PT, PhD

CONTACT

+3227642316gregory.reychler@uclouvain.be

William PONCIN, PT, PhD

CONTACT

william.poncin@uclouvain.be

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: All patients will receive standard physiotherapy as prescribed by the physician
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2019

First Posted

March 25, 2019

Study Start

August 1, 2019

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

April 29, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

BE(1)