NCT03887689

Brief Summary

The aim of the study is to translate and adapt a brief treatment protocol based on prolonged exposure provided within 72 hours after a rape to a Swedish context and pilot test feasibility and delivery in ten executive patients recruited at the Emergency Clinic for Rape victims in Stockholm.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2017

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 11, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 4, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 4, 2017

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

March 21, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 25, 2019

Completed
Last Updated

August 16, 2019

Status Verified

August 1, 2019

Enrollment Period

3 months

First QC Date

March 21, 2019

Last Update Submit

August 14, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • CLINICIAN-ADMINISTERED PTSD SCALE for Diagnostic and Statistical Manual of Mental Disorders-5 (CAPS)

    Clinical interview that gives a continuous measure of PTSD severity and dichotomous diagnosis of PTSD

    Change 2 months (primary endpoint) after intervention

Secondary Outcomes (7)

  • PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders-5 (PCL-5)

    Change 2 months after intervention

  • Beck Depression Inventory (BDI)

    Change 2 months after intervention

  • Adverse Events

    Change 2 months after intervention

  • WHO Disability Assessment Schedule (WHODAS)

    Change 2 months after intervention

  • Insomnia Severity Index (ISI)

    Change 2 months after intervention

  • +2 more secondary outcomes

Study Arms (1)

Modified prolonged exposure

EXPERIMENTAL

Participants will receive three sessions of modified prolonged exposure therapy.

Behavioral: Modified prolonged exposure

Interventions

Participants will receive three sessions of modified prolonged exposure therapy.

Modified prolonged exposure

Eligibility Criteria

Age18 Years+
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • At least 18 years of age
  • Attending at the Emergency Clinic for Rape victims at Stockholm South Hospital, Sweden within 72 hours after experiencing a rape)
  • Remembered the event.

You may not qualify if:

  • ongoing suicidal ideation or attempted suicide within the last two months
  • ongoing self-harm behavior
  • ongoing intoxication
  • other serious psychiatric comorbidity (ongoing psychotic symptoms or manic episode)
  • low cognitive capacity
  • not fluent in Swedish
  • subjected to ongoing violence or threat

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

March 21, 2019

First Posted

March 25, 2019

Study Start

January 11, 2017

Primary Completion

April 4, 2017

Study Completion

April 4, 2017

Last Updated

August 16, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share