NCT03883737

Brief Summary

Anterior knee pain (AKP) is one of the most frequent pathologies of the lower limb, in young and adult subjects. In the field of Physiotherapy, ultrasound-guided Percutaneous Neuromodulation (PNM) is defined as the application through a needle with ultrasound guidance of an electrical current at low or medium frequency, seeking a sensitive and / or motor response of a peripheral nerve in some point of its trajectory, or of a muscle in a motor point, with a therapeutic objective. The objective of this study is to analyze that the effect of PNM on the femoral nerve produces statistically significant changes in pain, joint range and knee functionality in patients with chronic AKP. Thirty subjects will be recruited, which will be divided into 2 groups: group 1 to which PNM will be applied to the femoral nerve of the pain knee; and group 2 to which PNM will be applied to the femoral nerve of the non-pain knee. The PNM intervention with NMP will consist in the single application of an asymmetric rectangular biphasic current (250 microseconds, 10 Hz)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 16, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 21, 2019

Completed
24 days until next milestone

Study Start

First participant enrolled

April 14, 2019

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 15, 2019

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2019

Completed
Last Updated

July 14, 2020

Status Verified

July 1, 2020

Enrollment Period

1 day

First QC Date

March 16, 2019

Last Update Submit

July 12, 2020

Conditions

Outcome Measures

Primary Outcomes (4)

  • visual analog scale (VAS) (0, no pain; 100, maximum pain).

    pain

    up to 1 week

  • range joint

    goniometer

    up to 1 week

  • VISA-p questionnaire (0, maximum pain; 100, no pain).

    Functional pain

    up to 1 week

  • Kujala questionnaire (0, maximum pain; 100, no pain).

    Functional pain

    up to 1 week

Study Arms (2)

Group 1: PNM in pain knee

EXPERIMENTAL

participants in whom PNM will be applied to the femoral nerve of the pain knee

Other: PNM

Group 2: PNM in non-pain knee

EXPERIMENTAL

participants in whom PNM will be applied to the femoral nerve of the non-pain knee

Other: PNM

Interventions

PNMOTHER

an asymmetric rectangular biphasic current (250 microseconds, 10 Hz)

Group 1: PNM in pain kneeGroup 2: PNM in non-pain knee

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • chronic anterior knee pain \>3 months
  • older than 18 years-old

You may not qualify if:

  • Surgical intervention in the intervention area
  • Prosthesis or osteosynthesis in the intervention area
  • Cardiac or tumoral diseases
  • Coagulopathies
  • Be under the effects of certain medications
  • contraindication characteristic of the puncture

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Seville

Seville, 41010, Spain

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

March 16, 2019

First Posted

March 21, 2019

Study Start

April 14, 2019

Primary Completion

April 15, 2019

Study Completion

November 1, 2019

Last Updated

July 14, 2020

Record last verified: 2020-07

Locations