Postoperative CRP Levels and Vaginal Cuff Hematoma

NCT03879499 | Completed

• 1 other identifier: 2017/78
• Study Type: observational
• Target: 106
• Locations: 0 countries
• Sites: N/A

Brief Summary

After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications. A total of 136 patients who underwent total laparoscopic hysterectomy (TLH) were evaluated. CRP, White blood cell (WBC) and hemoglobin values (Hb) were measured on the 1st, 2nd and 7th days before and after the operation. Complications, pre-postoperative vaginal length and female sexual function were evaluated. Fourteen patients who developed cuff hematoma during postoperative follow-up were analyzed with the receiver operating characteristics (ROC) curve. ROC curves with the largest area under the curve for each inflammatory marker were compared in order to define the marker with higher diagnostic accuracy.

Conditions

Postoperative Hematoma

Keywords

cuff hematoma; CRP levels

Outcome Measures

Primary Outcomes (2)

• Relationship between CRP Levels and cuff hematoma; crp levels

  The value of Postoperative CRP Levels to predict Postoperative Vaginal Cuff Hematoma ; To evaluate tissue trauma and surgical inflammatory responses, venous peripheral blood samples (C-reactive protein) were taken on the first, second and seventh day postoperatively. CRP values were measured under standardized conditions using turbidometry. CRP levels (mg / dl) were recorded.

  1 week

• Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement

  The patients were called to the outpatient clinic after the hysterectomy and evaluated by transvaginal ultrasonography (tvusg) for cuff hematoma.hematoma dimensions recorded in centimeters.

  15 days

Eligibility Criteria

• Age: 40 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

women who underwent TLH operation with benign gynecological indications

You may not qualify if:

• Decided to switch to laparotomy during operation
• postoperative complication due to relaparotomy
• infection (including urinary system and lung infections)
• Blood transfusion after TLH
• with rheumatic diseases
• length of hospital stay due to wound infection

Sponsors & Collaborators

• Kanuni Sultan Suleyman Training and Research Hospital: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: March 12, 2019
• First Posted: March 18, 2019
• Study Start: January 1, 2017
• Primary Completion: January 1, 2018
• Study Completion: January 1, 2018
• Last Updated: July 18, 2024

Record last verified: 2024-07