Using Smart Phone Technology to Support HIV Medication Refill Adherence in Virginia

NCT03876626 | Completed

• 1 other identifier: 21185
• Study Type: interventional
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to pilot a mobile health intervention, originally designed for HIV retention in care, for use in aiding patients with medication refills. The study will implement the PositiveLinks Rx app with the Henrico Health department. The study will assess user engagement and satisfaction with the app as well as preliminary impact on patient refill compliance.

Conditions

Hiv; Adherence, Medication

Outcome Measures

Primary Outcomes (1)

• Change in Patient Medication Refill Compliance

  Primary variable analysis will include examination of patient medication refill compliance at baseline and at the 6-month follow-up to assess for any change in refill compliance.

  Assessed at baseline and 6-months

Secondary Outcomes (8)

• App Usability

  30-days after enrollment

• Participant Check-In Engagement

  Assessed at 6-months

• Participant Messaging Engagement

  Assessed at 6-months

• Participant Community Engagement

  Assessed at 6-months

• Participant Feature Engagement

  Assessed at 6-months

Study Arms (2)

Provider Participants

OTHER

Employees who work with medication refills through the AIDS Drug Assistance Program at the Henrico Health Department will be invited to participate in the study as providers. Provider participants will receive access to a web based system that allows them to view information for their enrolled clients, securely message clients, and track medication refills. Providers will be asked to participate in a 30-day usability interview and a end-of-study assessment.

Other: PositiveLinks RX Portal

Patient Participants

OTHER

Clients who receive medication refills through the AIDS Drug Assistance Program at the Henrico Health Department will be invited to participate in the study as patients. Patient participants will be provided access to a mobile app that allows them to track their mood, stress, and medication adherence, access an anonymous online community, securely message providers, and receive medication refill alerts

Other: PositiveLinks RX Mobile App

Interventions

PositiveLinks RX Mobile App OTHER

A mobile app designed with tools to facilitate patient self-monitoring, patient-provider communication, medication refills, and social support.

Patient Participants

PositiveLinks RX Portal OTHER

An online portal that interacts with the mobile app to enable users to engage with participants though messaging and medication refill tracking.

Provider Participants

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Currently picking up of receiving medications through ADAP from the Henrico Health Department; Able to read in English; Able to speak English; Able to sign informed consent
• Current Henrico Health Department employee working with the ADAP pharmacy; Able to read in English; Able to speak English; Able to sign informed consent

You may not qualify if:

• Severe cognitive impairment that interferes with a subjects ability to consent; non-English speaking; Prisoners

Sponsors & Collaborators

• University of Virginia: lead
• Virginia Department of Health: collaborator

Study Sites (1)

Henrico Health Department

Richmond, Virginia, 23228, United States

Location

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome; Medication Adherence

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 25, 2019
• First Posted: March 15, 2019
• Study Start: March 21, 2019
• Primary Completion: September 21, 2019
• Study Completion: September 21, 2020
• Last Updated: July 14, 2025

Record last verified: 2025-07

Locations

US (1)