Epilepsy-related Brain Tumors Register

NCT03876093 | Withdrawn

• 1 other identifier: Epilepsy-related brain tumors
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

Epilepsy is defined by a cerebral disorder characterized by a lasting predisposition to generate epileptic seizures and by the neurobiological, cognitive, psychological and social consequences of this affection. The definition of epilepsy requires the occurrence of at least one epileptic seizure. 1% of the population suffers from epilepsy. The most common causes are genetic and vascular, 10% of epileptic syndromes are caused by a tumor. The incidence of brain tumors in people with epilepsy is approximately 4%. Among patients with brain tumor (s), the frequency of epilepsy is 30% or more depending on type of tumeur. 30-50% of brain tumors are revealed by an epileptic seizure and 10 to 30% of patients with brain tumor (s) will develop seizures during their evolution. The main objective is to evaluate the frequency of epileptic seizures according to the type of brain tumor.

Conditions

Epilepsy

Outcome Measures

Primary Outcomes (1)

• number of epileptic seizures

  number of epileptic seizures at the time of neurology consultation or hospitalization

  Day 1

Secondary Outcomes (1)

• number of epileptic seizures

  until 10 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients hospitalized following an epileptic seizure or seen in consultation in the neurology department of the GHPSJ, diagnosed with primary or secondary brain tumor from January 2013 to December 2023.

You may qualify if:

• patient whose age ≥ 18 years
• Patient hospitalized or seen in consultation in the Department of Neurology within the Hospital Group Paris Saint-Joseph
• Diagnosis of primary or secondary brain tumor, radiologically and / or histologically
• Epilepsy revealing or occurring in a patient developing a brain tumor
• Francophone patient

You may not qualify if:

• Pre-existing and known epilepsy before the diagnosis of brain tumors
• Epilepsy occurring within 2 weeks postoperatively
• Anteriority of taking antiepileptic treatment
• Patient under tutorship or curatorship
• Patient deprived of liberty
• Patient with comprehension disorders making it impossible to understand the protocol
• Patient or relative opposing the use of his data

Sponsors & Collaborators

• Fondation Hôpital Saint-Joseph: lead

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Roubeau Vincent, MD

  Fondation Hôpital Saint-Joseph

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2019
• First Posted: March 15, 2019
• Study Start: October 1, 2018
• Primary Completion: December 31, 2023
• Study Completion: June 30, 2024
• Last Updated: April 27, 2021

Record last verified: 2021-04