NCT03875768

Brief Summary

The goal of Nourish is to help adults with high blood pressure enjoy an eating pattern called DASH (Dietary Approaches to Stop Hypertension) to lower blood pressure and improve health. Nourish will use a mobile app and information about DASH to help study participants follow the DASH dietary plan by tracking what they eat and drink every day. The primary outcome of the study is 6-month change in following the DASH eating plan, as measured by 24-hour dietary recalls. The secondary outcome is change in blood pressure. Study participation will last one year.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
301

participants targeted

Target at P50-P75 for not_applicable hypertension

Timeline
Completed

Started Sep 2020

Typical duration for not_applicable hypertension

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 13, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 15, 2019

Completed
1.5 years until next milestone

Study Start

First participant enrolled

September 29, 2020

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 20, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 20, 2023

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

August 16, 2024

Completed
Last Updated

August 16, 2024

Status Verified

March 1, 2024

Enrollment Period

2.5 years

First QC Date

March 13, 2019

Results QC Date

March 13, 2024

Last Update Submit

March 13, 2024

Conditions

Keywords

Blood pressureHypertensionDASHNutritionDietary changeMobile healthDigital healthE-health

Outcome Measures

Primary Outcomes (1)

  • Change in Dietary Intake as Measured by Dietary Approaches to Stop Hypertension (DASH) Score

    Participants entered their dietary intake online via the National Cancer Institute's Automated Self-Administered 24-hour (ASA24) Dietary Assessment tool to record 2 separate 24-hour dietary recalls (1 weekday and 1 weekend day). DASH dietary nutrients are then converted into a score using the method described in Mellen et al (2008). Scores ranged from 0 to 9 where a higher score indicates better adherence to the DASH dietary pattern. Change in DASH score = 6-month DASH score - Baseline DASH score.

    Baseline and 6 months

Secondary Outcomes (2)

  • Change in Systolic Blood Pressure

    Baseline and 6 months

  • Change in Diastolic Blood Pressure

    Baseline and 6 months

Study Arms (2)

Intervention

EXPERIMENTAL

Participants will track their daily dietary intake for six months using an app and will receive automated feedback daily via text message based on DASH nutrients. Participants in-need of coaching based on their adherence to the key nutrients in the DASH dietary pattern or engagement in the intervention will receive responsive digital coaching from Nourish registered dietitians.

Behavioral: Tracking plus coaching

Control

NO INTERVENTION

Participants will receive information about the DASH dietary pattern and will track their daily dietary intake using an app for six months.

Interventions

Participants will track their nutrition intake every day for six months using a study app and receive tailored feedback via text message based on their nutritional intake and adherence to the DASH dietary pattern. If necessary, they will receive responsive coaching from a Nourish registered dietitian in order to increase adherence to the DASH dietary pattern and their engagement with the intervention.

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Systolic blood pressure of 120-159 mmHg or diastolic blood pressure of 80-99 mmHg, whether or not taking blood pressure medications.
  • BMI ≥ 18.5 kg/m2
  • Smartphone with a data plan
  • Willing to receive daily text messages
  • Valid email address
  • Willing and able to participate in online study videoconferencing visits (Zoom)
  • Lives in the U.S.
  • Reads and writes in English

You may not qualify if:

  • Participating in another related research study
  • Cardiovascular disease event (e.g. stroke, myocardial infarction) in prior 6 months
  • Bariatric surgery in the last 12 months or planned during the study period
  • Active cancer
  • Recent hospitalization due to psychiatric condition or event
  • Pregnancy- current or planned during the study period
  • Documented dementia
  • Lives with someone else participating in the Nourish study
  • To learn more about the study and to see if eligible to participate, visit www.nourishstudy.org

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Duke University Medical Center

Durham, North Carolina, 27708, United States

Location

MeSH Terms

Conditions

HypertensionHealth Behavior

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesBehavior

Results Point of Contact

Title
Gary G. Bennett, PhD
Organization
Duke University

Study Officials

  • Gary G. Bennett, PhD

    Duke University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 13, 2019

First Posted

March 15, 2019

Study Start

September 29, 2020

Primary Completion

March 20, 2023

Study Completion

March 20, 2023

Last Updated

August 16, 2024

Results First Posted

August 16, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share

Locations