Sweat and Gas Sensor for Healthy Skin and Atopic Dermatitis
Exploratory Study of Sweat Cytokines and Insensible Gas Losses From Skin in Healthy Normal Adults and Patients With Atopic Dermatitis
1 other identifier
observational
20
1 country
1
Brief Summary
Pilot study of a wearable gas and sweat skin sensor
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jan 2019
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 15, 2019
CompletedFirst Submitted
Initial submission to the registry
January 29, 2019
CompletedFirst Posted
Study publicly available on registry
March 14, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 10, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
August 10, 2021
CompletedApril 20, 2022
April 1, 2022
2.6 years
January 29, 2019
April 19, 2022
Conditions
Outcome Measures
Primary Outcomes (2)
Evaluation of gas exudates
Evaluation of protein contents from gas exudates from the skin
20 minutes
Evaluation of sweat proteins
Evaluation of protein contents from sweat from the skin
20 minutes
Study Arms (2)
Healthy Adults
Healthy adults with no prior diagnosis of atopic dermatitis
Atopic Dermatitis
Adults with prior diagnosis of Atopic Dermatitis from board certified dermatologist
Interventions
The gas sensor is an airtight gas capsule attached with a floating solid phase microextraction (SPME) tube. SPME uses a fiber coated with a nontoxic liquid (polymer), and a nontoxic solid (sorbent). The fiber coating extracts the compounds from the gas being released from the skin. Only the glass sample is in contact with the skin.
The sweat sensor is a soft, flexible device that rests on the skin and collects secreted sweat through capillary action. The device is held in place by medical-grade acrylic adhesive film.
Eligibility Criteria
Healthy adults and adults with prior diagnosis of atopic dermatitis from made by board certified dermatologist
You may qualify if:
- Age ≥18 years old
- Subjects willing and able to comply with requirements of the protocol
- Healthy adults or subjects with atopic dermatitis
You may not qualify if:
- Age \<18 years old
- Subjects unwilling and able to comply with requirements of the protocol
- History of skin allergy to medical adhesive tape
- History of heat stroke, heat related or exercise related
- Non-English speaking subjects
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Northwestern University
Chicago, Illinois, 60610-5402, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Shuai Xu, MD
Northwestern University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
January 29, 2019
First Posted
March 14, 2019
Study Start
January 15, 2019
Primary Completion
August 10, 2021
Study Completion
August 10, 2021
Last Updated
April 20, 2022
Record last verified: 2022-04