NCT03873454

Brief Summary

The hypothesis of this trial is that listening to music will decrease the stress levels that patients face as evidenced by their STAI scores, salivary cortisol levels and intra-operative autonomic parameters.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
139

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2014

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2014

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

August 12, 2014

Completed
4.6 years until next milestone

First Posted

Study publicly available on registry

March 13, 2019

Completed
Last Updated

March 13, 2019

Status Verified

March 1, 2019

Enrollment Period

2 months

First QC Date

August 12, 2014

Last Update Submit

March 11, 2019

Conditions

Keywords

cataract surgerymusicsalivary cortisol

Outcome Measures

Primary Outcomes (2)

  • Salivary Cortisol

    1 hour before the surgery a saliva sample was collected from the patient in order to test for salivary cortisol as a measure of stress.

    Pre-operatively

  • Salivary Cortisol

    10 minutes after the surgery, a saliva sample was collected from the patient in order to test for salivary cortisol as a measure of stress.

    10 minutes post-operatively

Study Arms (3)

Experimental Group

ACTIVE COMPARATOR

The experimental group listened to music and wore Sennheiser non-occlusive headphones

Device: Sennheiser non-occlusive headphones

Control 1 with no music

OTHER

This cohort wore non-occlusive earphones but did not listen to music

Device: Sennheiser non-occlusive headphones without music

Control 2 with no music

OTHER

The control 2 patients did not listen to music nor wore earphones.

Other: No Sennheiser non-occlusive headphones

Interventions

Patients listened to music of their choice using non-occlusive headphones

Experimental Group

Patients wore non-occlusive headphones but had no music playing

Control 1 with no music

Patients did not wear non-occlusive headphones and did not listen to music

Control 2 with no music

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Cataract surgery patients aged 50 years and above, with an acceptable hearing level based on CALFRAST hearing and the ability to wear clip-on on-ear headphones without discomfort. They were required to be mentally and physically capable of informed consent. Patients were also required to be ASA Grade 3 or lower.

You may not qualify if:

  • Severe/profound hearing impairments, patients with intellectual disabilities, patients on psychotropic medications or drugs affecting mood or hemodynamic status, ASA grade 4 and parturients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

National University Hospital

Singapore, 119074, Singapore

Location

Singapore National Eye Centre

Singapore, 168751, Singapore

Location

Study Officials

  • A/Prof Lian Kah Ti, MBBS, MMED

    National University Hospital, Singapore

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 12, 2014

First Posted

March 13, 2019

Study Start

May 1, 2014

Primary Completion

July 1, 2014

Study Completion

August 1, 2014

Last Updated

March 13, 2019

Record last verified: 2019-03

Locations