NCT03872245

Brief Summary

Patients will be randomized into 2 groups:

  • Group 1:Patients undergoing PENS T6, who also received Probiotics, during 10 weeks.
  • Group 2: Patients undergoing PENS T6 during 10 weeks. They will not received Probiotics Weight loss after 10 weeks of treatmente will be assessed.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Mar 2019

Shorter than P25 for phase_3

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 11, 2019

Completed
Same day until next milestone

Study Start

First participant enrolled

March 11, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 13, 2019

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2019

Completed
Last Updated

March 13, 2019

Status Verified

March 1, 2019

Enrollment Period

3 months

First QC Date

March 11, 2019

Last Update Submit

March 11, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Weight loss

    Weight loss after treatment will be assessed

    10 weeks

Study Arms (2)

PENS T6 + Probiotics

EXPERIMENTAL

The patients will receive Probiotics (Adomelle 1caps/12h) associated to PENS T6 during 10 weeks.

Biological: ProbioticsProcedure: PENS T6

PENS T6

ACTIVE COMPARATOR

The patients will undergo PENS T6 during 10 weeks.

Procedure: PENS T6

Interventions

ProbioticsBIOLOGICAL

The patients will receive Adomelle 1caps/12h during 10 weeks

PENS T6 + Probiotics
PENS T6PROCEDURE

The patients will undergo percutaneous electrical neurostimulation of dermatome T6 weekle, during 10 weeks

PENS T6PENS T6 + Probiotics

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • BMI \> 30 Kg/m2

You may not qualify if:

  • Patients with pacemakers or implanted electrical devices.
  • Pregnant women
  • History of allergy to Probiotics

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Weight Loss

Interventions

Probiotics

Condition Hierarchy (Ancestors)

Body Weight ChangesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Dietary SupplementsFoodDiet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Study Officials

  • Carolina Llavero

    Hospital Rey Juan Carlos

    STUDY DIRECTOR

Central Study Contacts

Jaime Ruiz-Tovar

CONTACT

Oscar Lorenzo

CONTACT

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Department of Surgery

Study Record Dates

First Submitted

March 11, 2019

First Posted

March 13, 2019

Study Start

March 11, 2019

Primary Completion

May 31, 2019

Study Completion

May 31, 2019

Last Updated

March 13, 2019

Record last verified: 2019-03