NCT03870269

Brief Summary

A prospective, randomized, controlled study designed to assess whether digital virtual reality (VR) models, created from existing CT scans and MRIs, provide surgeons with an improved understanding of their patients' anatomy, resulting in more efficient operations (robotic prostatectomy) and improved patient care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable prostate-cancer

Timeline
Completed

Started Feb 2019

Typical duration for not_applicable prostate-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 25, 2019

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

March 8, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 12, 2019

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2023

Completed
Last Updated

August 28, 2024

Status Verified

August 1, 2024

Enrollment Period

4.6 years

First QC Date

March 8, 2019

Last Update Submit

August 27, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Total operative time

    During procedure, not to exceed 12 hours

Secondary Outcomes (11)

  • Blood loss (measured in cubic centimeters)

    Measured at end of procedure, not to exceed 12 hours

  • Intraoperative conversion from robotic assisted laparoscopic procedure to open procedure

    During procedure, not to exceed 12 hours

  • Intraoperative complication

    During procedure, not to exceed 12 hours

  • Patient hospital stay

    Measured at time of patient discharge, up to 10 days

  • Positive tumor margin (assessed via standard post-operative biopsy)

    Measured 1-2 weeks after discharge

  • +6 more secondary outcomes

Study Arms (2)

Intervention Arm

EXPERIMENTAL

Subjects whose surgeon will be viewing VR models in addition to the source CT/MR image in connection with the case.

Device: Ceevra Reveal

Control Arm

NO INTERVENTION

Subjects whose surgeon will only be viewing CT/MR images in connection with the case.

Interventions

VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.

Intervention Arm

Eligibility Criteria

Age18 Years - 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient is undergoing robotic prostatectomy being performed by participating surgeon
  • Patient is willing to be randomized between intervention and control arms

You may not qualify if:

  • Patients with prior pelvic radiation
  • Patients with prior androgen deprivation therapy
  • Patients with prior localized ablative therapy
  • Patients with prior TURP or other surgical BPH treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UNC Hospital

Chapel Hill, North Carolina, 27514, United States

Location

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • Eric Wallen, MD

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 8, 2019

First Posted

March 12, 2019

Study Start

February 25, 2019

Primary Completion

September 30, 2023

Study Completion

September 30, 2023

Last Updated

August 28, 2024

Record last verified: 2024-08

Locations