Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements

NCT03868631 | Completed Results

• 1 other identifier: 01435225
• Study Type: interventional
• Target: 61
• Locations: 1 country
• Sites: 1

Brief Summary

Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis. The purpose of this study is to determine whether matching soy and whey protein supplements for leucine content instead of by total protein content would contribute to differences in strength increases and muscle growth in response to 12 wk of resistance training.

Conditions

Skeletal Muscle Growth

Outcome Measures

Primary Outcomes (3)

• Lean Body Mass Change

  assessed using dual energy x-ray absorptiometry (DEXA) scan for changes in lean body mass (kg)

  Post-12 week intervention

• Muscle Tissue Thickness Change

  assessed using changes in muscle thickness assessed by ultrasound (cm)

  Post-12 week intervention

• Leg Girth Changes

  assessed using circumference measurements (cm)

  Post-12 week intervention

Secondary Outcomes (1)

• Change in Peak Torque When Doing Leg Extensions

  Post-12 week intervention

Study Arms (2)

Soy protein group

ACTIVE COMPARATOR

Dietary Supplement: Soy protein supplement

Whey protein group

ACTIVE COMPARATOR

Dietary Supplement: Whey protein supplement

Interventions

Whey protein supplement DIETARY_SUPPLEMENT

19 g whey protein isolate (contains 2 g leucine) was consumed daily by one intervention group.

Whey protein group

Soy protein supplement DIETARY_SUPPLEMENT

26 g soy protein isolate (contains 2 g leucine) was consumed daily by the other intervention group.

Soy protein group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• non-smoking
• body mass index (BMI) 18.5-24.9
• recreationally active

You may not qualify if:

• participated in structured weight training during the previous 12 month
• vegetarian or vegan
• presence of chronic disease
• pregnant, postpartum up to six months, lactating, or intention to become pregnant
• allergy to whey or soy
• changes in body weight more than 10 pounds in the past three months

Sponsors & Collaborators

• Point Loma Nazarene University: lead

Study Sites (1)

Arizona State University

Phoenix, Arizona, 85004, United States

Location

Limitations and Caveats

1. No non-protein control (ex: placebo, maltodextrin) 2. No objective measurement of physical activity outside of the exercise intervention 3. No objective verification if the participants consumed protein powder on non-training days

Results Point of Contact

• Title: Dr. Heidi Lynch
• Organization: Point Loma Nazarene University

hlynch@pointloma.edu

619-806-3306

Study Officials

• Heidi Lynch, PhD

  Point Loma Nazarene University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 25, 2019
• First Posted: March 11, 2019
• Study Start: August 15, 2016
• Primary Completion: April 30, 2017
• Study Completion: April 30, 2017
• Last Updated: February 27, 2020
• Results First Posted: February 27, 2020

Record last verified: 2020-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)