NCT03867838

Brief Summary

The aim of this study is to show that a wearable compliant arm support consisting of inflatable bladders with adjustable straps to connect them to the waist and arm can meaningfully increase the reachable workspace of persons with post-stroke arm weakness.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 5, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 8, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

June 14, 2019

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 27, 2020

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2020

Completed
5 months until next milestone

Results Posted

Study results publicly available

February 23, 2021

Completed
Last Updated

February 23, 2021

Status Verified

February 1, 2021

Enrollment Period

11 months

First QC Date

March 5, 2019

Results QC Date

November 9, 2020

Last Update Submit

February 5, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percent Change From Baseline in Reachable Workspace

    Reachable workspace was measured using a PhaseSpace motion capture system, recorded as an area (in square meters).

    baseline, while using support device, and 30 minutes following removal of support device (up to 4 minutes per assessment)

Secondary Outcomes (1)

  • Percent Change From Baseline in Biceps Activation

    baseline and while using support device (up to 10 seconds per assessment)

Study Arms (1)

Stroke survivors

EXPERIMENTAL

Stroke survivors with upper extremity motor impairments

Device: compliant support

Interventions

Participants will be given compliant arm support and their reachable workspace measured

Stroke survivors

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • greater than 6 months post-stroke
  • passive abduction to 90 degrees at shoulder
  • reduced active (retro)flexion/extension at shoulder when abducted to 90 degrees
  • reduced active flexion/extension at elbow

You may not qualify if:

  • unable to give informed consent
  • unable to comprehend and follow instructions
  • have a condition (other than stroke) affecting sensorimotor function
  • show evidence of unilateral spatial neglect
  • unable to sit in a chair without armrests for 2 hours

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University CHARM Lab

Stanford, California, 94305, United States

Location

Related Publications (2)

  • Simpson CS, Okamura AM, and Hawkes EW. Exomuscle: An inflatable device for shoulder abduction support. 2017 IEEE International Conference on Robotics and Automation (ICRA) 2017; pp. 6651-6657.

    BACKGROUND
  • Simpson C, Huerta B, Sketch S, Lansberg M, Hawkes E, and Okamura A. Upper Extremity Exomuscle for Shoulder Abduction Support. IEEE Transactions on Medical Robotics and Bionics. 2020; 2(3):474-484.

    RESULT

Results Point of Contact

Title
Cole Simpson
Organization
Stanford University

Study Officials

  • Allison Okamura

    Stanford University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Mechanical Engineering

Study Record Dates

First Submitted

March 5, 2019

First Posted

March 8, 2019

Study Start

June 14, 2019

Primary Completion

April 27, 2020

Study Completion

October 1, 2020

Last Updated

February 23, 2021

Results First Posted

February 23, 2021

Record last verified: 2021-02

Data Sharing

IPD Sharing
Will not share

Locations