NCT03864380|Completed
Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort
MARETINE
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MARETINE
Sponsor study identifier
observational
29
1 country
1
Study Start
March 15, 2019
Actual (reported)Primary Completion
April 14, 2019
Actual (reported)Study Completion
May 6, 2019
Actual (reported)The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization. The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition. The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise. This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date. The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized. the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 6, 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 4, 2019
Actual (reported)March 6, 2019
Actual (reported)March 15, 2019
Actual (reported)April 14, 2019
Actual (reported)May 6, 2019
Actual (reported)Density of retinal vascular plexuses
Percentage, Measurement with OCT-A
up to 1 hour
Exams performed before (1 month maximum) and after the marathon (1 hour maximum) : Color retinography Optical Coherence Tomography - Angiography (OCT-A) Blood pressure measurement
Non mydriatic color retinography within 1 month before and within 1 hour after the marathon
Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon
Person running a marathon
Fondation A de Rothschild
Paris, 75019, France
Mauget-Faysse M, Arej N, Paternoster M, Zuber K, Derrien S, Thevenin S, Alonso AS, Salviat F, Lafolie J, Vasseur V. Retinal and choroidal blood flow variations after an endurance exercise: A real-life pilot study at the Paris Marathon. J Sci Med Sport. 2021 Nov;24(11):1100-1104. doi: 10.1016/j.jsams.2021.03.013. Epub 2021 Mar 30.
Martine MAUGET FAYSSE
Fondation A. de Rothschild
29 participants (actual enrollment reported by the registry).
First Submitted
March 4, 2019
First Posted
March 6, 2019
Study Start
March 15, 2019
Actual (reported)Comparing VR and Balance Exercises In Rehabilitation of Adolescent Athletes
Blood pressure measurement within 1 month before and within 1 hour after the marathon
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Primary Completion
April 14, 2019
Actual (reported)Study Completion
May 6, 2019
Actual (reported)Last Updated
May 7, 2019
Record last verified: 2019-05
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Source: ClinicalTrials.gov.
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