NCT03862664

Brief Summary

Recently, there are increasing reports about pulmonary complications within living liver donors postoperatively. In this retrospective study, the investigators will highlight the risk factors and incidence of pulmonary complication among living liver-donors in our center.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
124

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 6, 2019

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

February 25, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 5, 2019

Completed
27 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2019

Completed
Last Updated

March 5, 2019

Status Verified

February 1, 2019

Enrollment Period

2 months

First QC Date

February 25, 2019

Last Update Submit

March 1, 2019

Conditions

Complication of Anesthesia

Outcome Measures

Primary Outcomes (1)

  • The number of participants with postoperative respiratory complications

    Respiratory complications as pulmonary embolism, pleural effusion, pneumothorax, pneumonia, atelectasis, acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and transfusion-related acute lung injury (TRALI) will be considered when they are clinically evident.

    an average period of 3 year

Secondary Outcomes (2)

  • The average of ICU stay among patients

    an average period of 3 year

  • The average of hospital stay among patients

    an average period of 3 year

Interventions

Collection of dataPROCEDURE

The investigators will retrieve retrospectively the medical record of donors who underwent hepatic lobectomy for liver transplantation

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Donors who underwent hepatic lobectomy for liver transplantation

You may qualify if:

  • Excellent general physical and mental condition,
  • Free of chronic disease or
  • Previous major abdominal surgery,
  • Body mass index (BMI) \<28,
  • ABO blood group identical to recipients and
  • Negative for hepatitis B, C and human immunodeficiency viruses (HIV).

You may not qualify if:

  • ASA physical status\> II,
  • BMI\>28,
  • Psychiatric or mental retardation,
  • pregnant and nursing women or
  • Patients with significant laboratory abnormalities

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ain Shams University hospitals

Cairo, 11591, Egypt

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of Anesthesia

Study Record Dates

First Submitted

February 25, 2019

First Posted

March 5, 2019

Study Start

February 6, 2019

Primary Completion

April 1, 2019

Study Completion

May 1, 2019

Last Updated

March 5, 2019

Record last verified: 2019-02

Locations

EG(1)