NCT03859661

Brief Summary

A study to evaluate the palatability of a nutritional support biscuit (Fitabisc) in patients about to undergo colorectal surgery.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2015

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

January 24, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 11, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 11, 2017

Completed
1.5 years until next milestone

First Posted

Study publicly available on registry

March 1, 2019

Completed
Last Updated

March 1, 2019

Status Verified

February 1, 2019

Enrollment Period

1.8 years

First QC Date

January 24, 2017

Last Update Submit

February 27, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Adherence to dose

    Patients to keep a diary of their consumption

    10 days

  • Palatability of biscuit

    Study will measure palatability on a standard Likert scale after 10 days

    10 days

Secondary Outcomes (2)

  • Progress of patients following surgery

    4-6 weeks post op.

  • Collection of events that might be associated with the ingredients of the biscuit.

    4-6 weeks post op.

Interventions

FitabiscDIETARY_SUPPLEMENT

Fitabisc is a chocolate cookie with vanilla cream filling which contains the most important antioxidants Vitamin C, Vitamin E, and the mineral Selenium. Fitabisc is not commercially available and for the purposes of this study it will be manufactured by Calerrific Ltd, which already produces a biscuit called CalBisc 100 as a simple calorie and nutritional supplement. Production takes place in a BRC Global Standard Grade A certified bakery operated by Farringford Foods in Portadown, Northern Ireland.

Eligibility Criteria

Age16 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients between the ages of 16 and 80 years inclusive.
  • Patients who are having colorectal surgery.
  • Patients who are able to give voluntary, written informed consent to participate in the study and from whom written consent has been obtained.

You may not qualify if:

  • Those who cannot or do not provide informed consent
  • Patients with a known or suspected allergy to any of the ingredients of Fitabisc e.g. gluten or dairy products
  • Patients with one of the following co-morbidities:
  • Haemochromatosis
  • Thalassaemia
  • Kidney disease
  • Liver disease
  • Reye syndrome
  • Patients who already take supplements of vitamin C, E, selenium or glutamine.
  • Patients with type 1 diabetes, or type 2 diabetes that requires them to have insulin or a hypoglycaemic drug such as Metformin.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

York Teaching Hospital NHS Foundation Trust

York, YO31 8HE, United Kingdom

Location

Study Officials

  • John Macfie, MBChB, MD

    York Teaching Hospital NHS Foundation Trust

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 24, 2017

First Posted

March 1, 2019

Study Start

December 1, 2015

Primary Completion

September 11, 2017

Study Completion

September 11, 2017

Last Updated

March 1, 2019

Record last verified: 2019-02

Locations