NCT03856346

Brief Summary

The aim of the study is to evaluate the degree of refractive error postoperatively in combined procedures and to calculate a new constant in order to improve current state of the art biometry calculations.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 5, 2019

Completed
22 days until next milestone

First Posted

Study publicly available on registry

February 27, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

June 1, 2019

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2020

Completed
Last Updated

May 2, 2019

Status Verified

April 1, 2019

Enrollment Period

1.1 years

First QC Date

February 5, 2019

Last Update Submit

April 30, 2019

Conditions

Keywords

VitrectomyPhacoemulsificationBiometryIOL calculationCataract

Outcome Measures

Primary Outcomes (4)

  • Refractive prediction error (measured by subjective refraction, in diopters)

    postoperative actual subjective refraction minus preoperative planned refraction in spherical equivalence (in diopters)

    6 weeks postoperatively

  • Absolute prediction error (measured by subjective refraction, in diopters)

    absolute value of the difference between postoperative actual refraction and preoperative planned refraction (in diopters)

    6 weeks postoperatively

  • Changes in Axial Length (measured by biometry, in milimeters)

    Change of axial length postoperatively (in milimeter)

    6 weeks postoperatively

  • Changes in corneal curvature (measured by corneal topography, in diopters)

    change in corneal curvature (in diopters)

    6 weeks postoperatively

Study Arms (1)

Phaco-vitrectomy

Diagnostic Test: Biometry

Interventions

BiometryDIAGNOSTIC_TEST

Biometry for phaco-vitrectomy procedures pre- and postoperatively

Phaco-vitrectomy

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients who undergo a combined procedure with phacoemulsification and pars plana vitrectomy

You may qualify if:

  • Patients who undergo a combined procedure with phacoemulsification and pars plana vitrectomy

You may not qualify if:

  • Sulcus fixation of the IOL, sulcus suture of the IOL, or intra-scleral IOL fixation because of intraoperative posterior capsule rupture
  • corneal disease, such as keratoconus, that interfered with refractive results
  • IOL implantation with a toric IOL or multifocal IOL
  • History of previous vitrectomy or corneal transplantation
  • Other coexisting ocular disease such as proliferative diabetic retinopathy, advanced age-related macular degeneration, uveitis, acute retinal necrosis, Coat's disease, proliferative vitreous retinopathy, or trauma
  • Intraocular tamponade using silicon oil

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cantonal Hospital of Sankt Gallen

Sankt Gallen, 9007, Switzerland

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Consultant ophthalmic surgeon

Study Record Dates

First Submitted

February 5, 2019

First Posted

February 27, 2019

Study Start

June 1, 2019

Primary Completion

June 30, 2020

Study Completion

September 30, 2020

Last Updated

May 2, 2019

Record last verified: 2019-04

Data Sharing

IPD Sharing
Will not share

Locations