NCT03856086

Brief Summary

This study will help the researchers find out whether the S+C approach is better, the same as, or worse than EUC.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 25, 2019

Completed
Same day until next milestone

Study Start

First participant enrolled

February 25, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 27, 2019

Completed
6.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 12, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 12, 2025

Completed
Last Updated

November 14, 2025

Status Verified

November 1, 2025

Enrollment Period

6.7 years

First QC Date

February 25, 2019

Last Update Submit

November 13, 2025

Conditions

Keywords

Comparing Distress ScreeningConsultation With Enhanced Usual CareSupportive care18-539

Outcome Measures

Primary Outcomes (1)

  • Number of Informal caregivers with unmet needs

    comparing the 3-month change scores on the NCCN problem list from baseline

    1 year

Study Arms (2)

Enhanced usual care (EUC)

ACTIVE COMPARATOR

ICs randomized to EUC following baseline questionnaire completion will be given instructions (Appendix I) on how to access or create an account to access the myMSK online portal IC Resources page (https://my.mskcc.org/login). If the caregiver does not wish to enroll in MyMSK, the research study staff will send them an email with sample referral material ( Appendix D. The IC Resources page includes links to extant MSK educational materials for ICs (e.g., "A Guide for Caregivers" \[47\]), contact information for psychosocial services (e.g., Caregivers Clinic in the MSK Counseling Center), and external resources (e.g., educational materials and services through the CSC, American Cancer Society, and others) (Appendix D,).

Behavioral: Baseline questionnaireBehavioral: NCCN Problem ListBehavioral: FACT-GPBehavioral: HADS

CancerSupportSource-CG screening plus consultation (S+C)

EXPERIMENTAL

ICs randomized to S+C will complete the web-based CSS-CG (Appendix C) using a tablet immediately following baseline study measures. In case of technical issues, ICs may complete Appendix C with the guidance of a member of the research study team. The CSS-CG asks ICs to rate their level of concern for 33 different possible problems: if a need is rated as low (i.e., "A little" or less concern), after each problem is rated ICs will be prompted to request pertinent educational materials if they are interested. If a need is endorsed (i.e., "Moderate" or greater concern), ICs are asked through the web-based electronic platform (https://mskcc.mycarereport.com) whether they would like educational materials and/or to speak with someone about that need (i.e., receive a referral).

Behavioral: Baseline questionnaireBehavioral: NCCN Problem ListBehavioral: FACT-GPBehavioral: HADSBehavioral: CSS-CG

Interventions

Baseline questionnaire on the day of the patient's surgery.

CancerSupportSource-CG screening plus consultation (S+C)Enhanced usual care (EUC)

NCCN Distress Thermometer

CancerSupportSource-CG screening plus consultation (S+C)Enhanced usual care (EUC)
FACT-GPBEHAVIORAL

Greater overall quality of life

CancerSupportSource-CG screening plus consultation (S+C)Enhanced usual care (EUC)
HADSBEHAVIORAL

Lower anxiety and depression

CancerSupportSource-CG screening plus consultation (S+C)Enhanced usual care (EUC)
CSS-CGBEHAVIORAL

web-based CSS-CG

CancerSupportSource-CG screening plus consultation (S+C)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-identified caregiver to a patient receiving surgery at JRSC OR self-identified caregiver to a patient at various inpatient surgical floors (i.e., M4, M7, M8) at the Main Hospital OR self-identified caregiver to a patient at the BMT clinic.
  • English fluency: Self-report by subject identifying English as the preferred language for healthcare, and self-reported degree of fluency as speaking English "Very well."
  • years old or older as per self report
  • Agree to fulfill responsibilities as an IC during the perioperative phases as per self report

You may not qualify if:

  • Cognitive difficulties that preclude participation in the intervention or accurate assessment in the judgment of the PI
  • Medical illness that is of sufficient severity to preclude further participation in the study.
  • Presenting to JRSC as the IC for a patient undergoing a prophylactic procedure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States

Location

Related Links

MeSH Terms

Interventions

Surveys and Questionnaires4-amino-4'-hydroxylaminodiphenylsulfone

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Officials

  • Allison Applebaum, PhD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Participants will be randomized between screening with the CSS-CG + consultation (S+C, and enhanced usual care.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 25, 2019

First Posted

February 27, 2019

Study Start

February 25, 2019

Primary Completion

November 12, 2025

Study Completion

November 12, 2025

Last Updated

November 14, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will share

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Shared Documents
SAP, ICF

Locations