NCT03850327

Brief Summary

The objective of the study is to confirm the safety and efficacy of the BIOMONITOR III system. Furthermore, the insertion procedure, the use and handling of the incision and insertion tools and the sensing quality of the BIOMONITOR III will be assessed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at below P25 for not_applicable atrial-fibrillation

Timeline
Completed

Started Mar 2019

Shorter than P25 for not_applicable atrial-fibrillation

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 11, 2019

Completed
10 days until next milestone

First Posted

Study publicly available on registry

February 21, 2019

Completed
15 days until next milestone

Study Start

First participant enrolled

March 8, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 6, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 6, 2019

Completed
Last Updated

May 27, 2021

Status Verified

December 1, 2018

Enrollment Period

7 months

First QC Date

February 11, 2019

Last Update Submit

May 26, 2021

Conditions

Keywords

Implantable Cardiac Monitor

Outcome Measures

Primary Outcomes (2)

  • Adverse Events

    (procedure / device related)

    1 month

  • R-wave amplitude

    1 month

Secondary Outcomes (1)

  • Insertion procedure of the BIOMONITOR III by using the incision and insertion tools

    At the day of insertion of the BIOMONITOR III

Study Arms (1)

BIOMONITOR III

EXPERIMENTAL
Device: BIOMONITOR III

Interventions

Patients with ICM indication receive a third-generation implantable cardiac monitor

BIOMONITOR III

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient is at high risk of developing a clinically important cardiac arrhythmia; or Patient is undergoing investigation for symptoms such as palpitations, pre-syncope or syncope, that are suggestive of an underlying cardiac arrhythmia; or Patient is undergoing investigation for the detection of atrial fibrillation following cryptogenic stroke; or Patient is planned for AF ablative procedure or has already undergone an AF ablative procedure.
  • Patient is able to understand the nature of study and has provided written informed consent.
  • Patient is willing and able to perform all follow up visits at the study site.
  • Patient is willing and able to use the CardioMessenger and accepts the BIOTRONIK Home Monitoring concept.

You may not qualify if:

  • Patients implanted with ICD or pacemaker.
  • Patient is pregnant or breast feeding.
  • Patient is less than 18 years old.
  • Patient is participating in another interventional clinical investigation
  • Patient´s life-expectancy is less than 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

HeartCare Partners - Wesley Testing

Auchenflower, Queensland, 4066, Australia

Location

Bundaberg Cardiology

Bundaberg, Queensland, 4670, Australia

Location

Princess Alexandra Hospital

Woolloongabba, Queensland, 4102, Australia

Location

HeartCare Victoria - Doncaster

Balwyn, Victoria, 3103, Australia

Location

Mount Hospital

Perth, Western Australia, 6000, Australia

Location

The Canberra Hospital

Canberra, 2605, Australia

Location

The Alfred Hospital

Melbourne, 3004, Australia

Location

MeSH Terms

Conditions

Atrial FibrillationSyncopeTachycardia

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsUnconsciousnessConsciousness DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsCardiac Conduction System Disease

Study Officials

  • Olivier van den Brink, Dr.

    The Alfred Hospital, Melbourne, Australia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 11, 2019

First Posted

February 21, 2019

Study Start

March 8, 2019

Primary Completion

October 6, 2019

Study Completion

October 6, 2019

Last Updated

May 27, 2021

Record last verified: 2018-12

Locations