Impacts of Aquatic vs Land Walking on Vascular Health and Exercise Tolerance in Patients With Peripheral Artery Disease

NCT03849300 | Completed Results

• 1 other identifier: UNOmaha5
• Study Type: interventional
• Target: 147
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study was to examine the impacts of a 12-week aquatic walking exercise program on body composition, vascular function, cardiorespiratory capacity, exercise tolerance, muscular strength, and physical function in patients with peripheral artery disease (PAD). The effects of the 12-week aquatic walking exercise program were also compared to the effects of a 12-week land-based walking exercise program.

Conditions

Peripheral Artery Disease; Vascular Function; Exercise Tolerance; Peripheral Arterial Disease

Keywords

arterial stiffness; cardiorespiratory capacity; exercise tolerance; VO2max

Outcome Measures

Primary Outcomes (1)

• Peripheral Arterial Stiffness

  Peripheral arterial stiffness was estimated as measurement of femoral-to-ankle pulse wave velocity (meters per second). A higher value represents a worse outcome. Scale range is approximately 7.0 - 14.0 meters per second for healthy populations.

  12 weeks

Secondary Outcomes (13)

• Body Composition

  12 weeks

• Resting Heart Rate

  12 weeks

• Systolic Blood Pressure

  12 weeks

• Resting Metabolic Rate

  12 weeks

• Cardiorespiratory Capacity

  12 weeks

Study Arms (4)

Control Group

NO INTERVENTION

No exercise intervention

Aquatic walking exercise group 1

EXPERIMENTAL

The aquatic walking exercise program was performed for 60 minutes per day, 4 times per week for 12 weeks. The program consisted of a warm-up (10 min) and cool-down (10 min) which included stretching and gait training. The 40-minute main exercise session included 10 minutes of hip flexion-extension, hip abduction-adduction, and knee flexion-extension. The last 30 minutes included water walking (forward, backward). The program intensity was established using heart rate reserve (HRR). Weeks 1-4 were at 50-60% HRR, weeks 5-8 were at 60-70% HRR, and weeks 9-12 were at 70-85% HRR. Subjects wore a heart rate monitor during the whole exercise training session in order to maintain the designated training intensity.

Other: Aquatic walking exercise program group 1

Aquatic walking exercise group 2

EXPERIMENTAL

The aquatic walking exercise program was performed for 60 minutes per day, 4 times per week for 12 weeks. The program consisted of a warm-up (10 min) and cool-down (10 min) which included stretching and gait training. The 40-minute main exercise session included 10 minutes of hip flexion-extension, hip abduction-adduction, and knee flexion-extension. The last 30 minutes included water walking (forward, backward). The program intensity was established using heart rate reserve (HRR). Weeks 1-4 were at 50-60% HRR, weeks 5-8 were at 60-70% HRR, and weeks 9-12 were at 70-85% HRR. Subjects wore a heart rate monitor during the whole exercise training session in order to maintain the designated training intensity.

Other: Aquatic walking exercise program group 2

Land-based walking exercise group

ACTIVE COMPARATOR

The land-based walking exercise program was performed for 60 minutes per day, 4 times per week for 12 weeks. The program consisted of a warm-up (10 min) and cool-down (10 min) which included stretching and gait training. The 40-minute main exercise session included 10 minutes of low-intensity forward, backward, and lateral side-stepping movements on flat group. The remaining 30 minutes included treadmill walking exercise. The program intensity was established using heart rate reserve (HRR). Weeks 1-4 were at 50-60% HRR, weeks 5-8 were at 60-70% HRR, and weeks 9-12 were at 70-85% HRR. Subjects wore a heart rate monitor during the whole exercise training session in order to maintain the designated training intensity.

Other: Land-based walking exercise group

Interventions

Aquatic walking exercise program group 1 OTHER

12 week aquatic walking exercise program

Aquatic walking exercise group 1

Aquatic walking exercise program group 2 OTHER

12 week aquatic walking exercise program

Aquatic walking exercise group 2

Land-based walking exercise group OTHER

12 week land-based walking exercise program

Land-based walking exercise group

Eligibility Criteria

• Age: 50 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Peripheral artery disease (ankle-brachial index between 0.6 and 0.9)
• years of age
• Sedentary (less than 1 hour of regular exercise participation per week within the previous year)

You may not qualify if:

• current smoker (smoking within previous 6 months)
• psychiatric conditions
• pulmonary disease
• renal disease
• thyroid disease

Sponsors & Collaborators

• Pusan National University: lead
• Marymount University: collaborator
• Dong-Eui University: collaborator

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

Atherosclerosis; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases; Peripheral Vascular Diseases

Results Point of Contact

• Title: Dr. Song-Young Park
• Organization: The University of Nebraska at Omaha

song-youngpark@unomaha.edu

402-554-3374

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: aquatic walking exercise intervention group 1 vs. control group; aquatic walking exercise intervention group 2 vs. land-based walking exercise group

Study Record Dates

• First Submitted: February 19, 2019
• First Posted: February 21, 2019
• Study Start: May 9, 2010
• Primary Completion: August 8, 2017
• Study Completion: February 4, 2019
• Last Updated: November 3, 2020
• Results First Posted: March 9, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share