NCT03847012

Brief Summary

The purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with coronary artery diseases (CAD) and to compare the effects of blood pressure responses after exercise training. The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. The subjects performed the treadmill or stationary bicycle exercise randomly.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable coronary-artery-disease

Timeline
Completed

Started Mar 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 10, 2019

Completed
10 days until next milestone

First Posted

Study publicly available on registry

February 20, 2019

Completed
19 days until next milestone

Study Start

First participant enrolled

March 11, 2019

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2020

Completed
Last Updated

April 8, 2021

Status Verified

April 1, 2021

Enrollment Period

1.6 years

First QC Date

February 10, 2019

Last Update Submit

April 7, 2021

Conditions

Keywords

coronary artery diseaseblood pressurerehabilitationexercise mode

Outcome Measures

Primary Outcomes (2)

  • heart rate

    heart rate

    Change from baseline heart rate at 6 weeks

  • blood pressure

    blood pressure

    Change from baseline blood pressure at 6 weeks

Secondary Outcomes (2)

  • perceived exertion scale

    baseline and 6 weeks

  • heart rate variability

    baseline and 6 weeks

Other Outcomes (6)

  • age

    baseline

  • gender

    baseline

  • risk level of exercise

    baseline

  • +3 more other outcomes

Study Arms (1)

patients with coronary artery diseases

EXPERIMENTAL

The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. After at least 3 times of familiar with the cardiopulmonary rehabilitation training machine, the subjects performed the treadmill or stationary bicycle and exercise to personalized target heart rate for 10 minutes, take a rest until the heart rate recover to the resting heart rate, and then repeated the exercise in another exercise mode.

Other: exercise

Interventions

The test order will be random. After at least 12 times of cardiopulmonary rehabilitation training, the test will be performed again.

patients with coronary artery diseases

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients with coronary artery diseases who are referred to phase II cardiopulmonary rehabilitation exercise training.

You may not qualify if:

  • patients with non-coronary artery diseases
  • atrial fibrillation
  • neurological or musculoskeletal problems

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 100, Taiwan

Location

MeSH Terms

Conditions

Coronary Artery Disease

Interventions

Exercise

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2019

First Posted

February 20, 2019

Study Start

March 11, 2019

Primary Completion

September 30, 2020

Study Completion

September 30, 2020

Last Updated

April 8, 2021

Record last verified: 2021-04

Data Sharing

IPD Sharing
Will not share

Locations